Development of Acne Patches from Molineria latifolia Herb. ex Kurz Root Extract Containing Antioxidant and Antibacterial Effects
Keywords:
Molineria latifolia Herb. ex kurz root, acne patches, antioxidant activity, antibacterial activityAbstract
This experimental study aimed to investigate the biological properties of the extract from Molineria latifolia Herb ex Kurz. and develop an acne treatment patch product. The samples of M. latifolia were randomly collected from Phatthalung province. Descriptive statistics were used to analyze the data, including percentages and means. The extracts from M. latifolia were tested for an inhibition effect on the C. acne bacteria, antioxidant activity, patch elasticity, and physical characteristics of the acne patch. A total of five formulations were developed. The result revealed that a formula containing pectin, sodium carboxymethyl cellulose (NaCMC), glycerol, and M. latifolia root extract was the best in terms of inhibiting C. acne bacteria and having an antioxidant activity with an IC50 value of 15.70 µg/mL, and the elasticity value of the patch was -24.22 mm. The acne patch containing the extract from M. latifolia Herb. exhibited a soft texture, excellent elasticity, and a long period for skin adherence and maintained its physical properties without changes in odor or pH (ranging from 5.38 to 7), which meets the standard for products used on human facial skin. Additionally, the patch is convenient for carrying and using for individuals facing acne problems.
References
Buachoon, N., & Klomsungcharoen, W. (2024). Antioxidant activity and Tyrosinase inhibition activity of extracts from Elaeocarpus hygrophilus to cosmetic formulations for continue commercialization. EAU Heritage Journal Science and Technology, 18(3), 37–54. Retrieved from https://he01.tci-thaijo.org/index.php/EAUHJSci/article/view/270571 (in Thai)
Buachoon, N. (2020). Phytochemical screening and antioxidant activity of fresh and dried Nasturtium officinal Plants. EAU Heritage Journal Science and Technology, 14(1), 144–154. Retrieved from https://he01.tci-thaijo.org/index.php/EAUHJSci/article/view/240121 (in Thai)
Charoenphonphibun, K., Chaichalotrakul, S., & Saiwichai, T. (2018). Effectiveness of a non-thermal plasma machine in treating acne on the back. Journal of the Graduate Research Presentation Conference, 61(13), 3042. Retrieved from https://rsujournals.rsu.ac.th/index.php/rgrc/issue/view/40 (in Thai)
Chotinukul, T., Soi-ngam, T., Chunhachat, O., & Srithaworn, M. (2021). Development of acne treatment patches from natural materials: Biocellulose mixed with red sandalwood rough extracts. Thai Science and Technology Journal (TSTJ), 29(6), 967-976. Retrieved from https://li01.tci-thaijo.org/index.php/tstj/article/view/247182/173597 (in Thai)
Frezza, E. (2017). Medicated hydrocolloid dressing for acne treatment (Record no. US 2017/ 0304215 A1). USA: United States Patent. https://bit.ly/3XeGXFM
Heyneman, A., Beele, H., Vanderwee, K., & Defloor, T. (2008). A systematic review of the use of hydrocolloids in the treatment of pressure ulcers. Journal of Clinical Nursing, 17(9), 1164–1173. https://doi.org/10.1111/j.1365-2702.2007.02218.x
Inprasert, S., Pithak Saeheng, P., Petcharee, P., Dechbumroong, P., Anuntawuttikul, K., Niwattisaiwong, N., & Suedee, A. (2022). Gel formulation from bark of Tinospora crispa (L.) Miers ex Hook. F. & Thomson extract for inflammatory acne. Journal of Science and Technology Mahasarakham University, 41(2), 104-116. Retrieved from https://li01.tci-thaijo.org/index.php/scimsujournal/article/view/253056/174012 (in Thai)
Jaricksakulchai, J., Sillaparassamee, R., & Wiangpati, T. (2023). Skin cream containing Ganoderma lucidum root extract to increase skin elasticity in the elderly, Sa Kaeo Province. EAU Heritage Journal Science and Technology, 17(1), 41–51. Retrieved from https://he01.tci-thaijo.org/index.php/EAUHJSci/article/view/259638 (in Thai)
Jittsomnuek, I., & Akapanchai, D. (2021). Effectiveness of hydrogel mixed with Phak Buran extract in reducing acne inflammation. Journal of Health Systems Research and Development, 14(3), 111-124. Retrieved from https://kb.hsri.or.th/dspace/handle/11228/5254 (in Thai)
Kapao, N., & Wattanutchariya, W. (2018). Development of natural acne patch from local materials using quality function deployment technique. In C. Hamontree (Ed.). Proceedings of the 4th International Conference on Engineering, Applied Sciences and Technology (ICEAST 2018): Exploring Innovative Solutions for Smart Society 2018 Jul 4-7 Phuket, Thailand (pp. 201-204). Phuket: Curran. (in Thai)
Luengnarudom, U., Akkanimat, R., Srirat, P., Pratumthet, C., Nakasen, K., Inthaketu, R., & Phromchiang, J. (2022). Development of wound dressing hydrocolloid patch of Garcinia mangostana Linn. extracts. Koch Cha Sarn Journal of Science, 44(1), 51–61. Retrieved from https://li01.tci-thaijo.org/index.php/kochasarn/article/view/256534 (in Thai)
Nakawajana, S., Srisuphasitanon, S., Sukatta, U., Sukhyai, P., & Piyaboon., O. (2020). Anti-Staphylococcus epidermidis acnes by bio-cellulose acne patches from mangosteen peel extracts. Journal of Health Science of Thailand, 29(4), 711–718. Retrieved from https://thaidj.org/index.php/JHS/article/view/9315 (in Thai)
Napisah, H., Azmahani, A., Zubaidi, A. L., Intan, A., & Nazifah, A. (2011). A Preliminary Study on the Antimicrobial Properties of Several Plants Collected from Terengganu, Malaysia. Journal Of Agrobiotechnology, 2, 99-106. Retrieved from https://journal.unisza.edu.my/agrobiotechnology/index.phpagrobiotechnology/article/view/22
Pansawat, N., Chuthong, L., and Akrasiritratana, K., (2023). Development of skin patches from herbal compress extracts. Valaya Alongkorn Research and Development Journal under Royal Patronage, 18(2), 2-14. Retrieved from https://so06.tci-thaijo.org/index.php/vrurdistjournal/article/view/258114/178176 (in Thai)
Pirunrat Saelim. (2012). Article from Faculty of Medicine, Prince of Songkla University. Retrieved from https://www.ttmed.psu.ac.th/thblog/113 (in Thai)
Prasertwaree, P., Mingmuang, J., Thongdee, S., Onthong, S., & Chansuwanich, N. (2015). The Development of Transdermal Patch From Centella asiatica (L.) Urban. Bulletin of the Department of Medical Sciences, 57(2), 174–185. Retrieved from https://he02.tci-thaijo.org/index.php/dmsc/article/view/242715 (in Thai)
Pochananukit, N., & Kajonchipphanngam, S., (2010). Herbal gel for inhibiting acne-causing bacteria. Ladkrabang Science Journal, 19(2), 48-58. Retrieved from https://li01.tci-thaijo.org/index.php/science_kmitl/article/view/100105/77805 (in Thai)
Saenprakob, P., & Saengmanee, K., (2020). Development of an anti-acne facial cleansing gel formula using Thai anchor extract. Wichcha Journal, 39(2), 87-100. Retrieved from https://li01.tci-thaijo.org/index.php/wichcha/article/view/237057/169773 (in Thai)
Sillaparassamee, R., Jaricksakulchai, J., & Praserttai, C. (2023). Development of body scrub cream from palm kernel meal. EAU Heritage Journal Science and Technology, 17(1), 201–212. Retrieved from https://he01.tci-thaijo.org/index.php/EAUHJSci/article/view/259641 (in Thai)
Sillaparassamee, R., Jaricksakulchai, J., Kalapakdee, N., Kalapakdee, P., Srichan, N., & Praibueng, T. (2022). Effect of preparation of moringa seeds tea by hot air and freeze drying methods on antioxidant activity by DPPH assay. EAU Heritage Journal Science and Technology, 16(2), 105–118. Retrieved from https://he01.tci-thaijo.org/index.php/EAUHJSci/article/view/255214 (in Thai)
Teerapattanawong, P., Oon-on, W., & Kaewbutra, S., (2023). Testing for phytochemical components. Total phenolic compounds and antioxidant activity of plai, turmeric, and ginger extracted using the soaking and fermentation technique in different solvents. Health Science, Science and Technology Review, 16(3), 54-69. Retrieved from https://li01.tci-thaijo.org/index.php/journalup/article/view/259852 (in Thai)
Thadachaipongsathorn, N., Kahakitpaisarn, I., Kongwanich, K., & Piyaboon, O. (2022). Effcacy of lemon peel patch with Caesalpinia sappan heartwood crude extracts in inhibiting acne causing Bacteria Staphylococcus aureus. Journal of Health Science of Thailand, 31(6), 1132–1139. Retrieved from https://thaidj.org/index.php/JHS/article/view/13001 (in Thai)
Wongkhattiya, N., Hanprasert, T., Sanguansermsri, P., Kawaree, Fraser, L. H., & Sanguansermsri., D. (2016). Effects of Mahahong essential oils in inhibiting bacteria that cause acne. Naresuan University Journal: Science and Technology (NUJST), 24(3), 25-31. Retrieved from https://www.thaiscience.info/Journals/Article/NUST/10984954.pdf (in Thai)
