Pain Relief in Neonates undergoing Venipuncture between Breast Milk and Sucrose Solution
Pain Relief in Neonates undergoing Venipuncture
Keywords:
neonate, painful shoulder, analgesia, breast milk, sucrose solutionAbstract
All neonates experience pain from medical procedures. Without effective pain management, it can lead to adverse sequelae and also causes parental concerns. The aim of this study was to compare analgesic effect of breast milk and sucrose solution on neonates undergoing venipuncture. A double-blind, randomized controlled trial was conducted during June 1, 2019 to April 30, 2020 in healthy neonates in Buddhachinaraj Phitsanulok Hospital. A total of 108 neonates were randomized, 54 neonates in each group. Median (Q1, Q3) of Neonatal Infant Pain Scale (NIPS) at time of venipuncture, 1 minute and 3 minutes after venipuncture were 7 (6, 7), 3 (0, 6), and 0 in breast milk group and 3.5 (2, 6), 0, and 0 in sucrose solution group. Median (Q1, Q3) of duration of crying were 49.5 (22.6, 87.0) and 0 (0, 22.8) seconds in breast milk group, and sucrose solution group respectively. Median of NIPS and duration of crying were significant lower in sucrose solution groups (p < 0.001). In conclusion, sucrose solution has more analgesic effect than breast milk in healthy neonates during and after venipuncture
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