Effect of the Behavioral Economics Based Measure to Contain Antibiotics Use: A Case of a General Hospital in Pattani
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Abstract
Objective: To evaluate the effect of behavioral economics based measure to contain antibiotics use by comparing antibiotic prescribing rate and expenditure before and after intervention. Methods: This study was pre-post single group quasi-experimental research assessing effectiveness of the intervention based on behavioral economics. Intervention was feedback to each individual prescriber on his/her antibiotic prescribing rate with two different feedback frequencies, i.e. quarterly feedback for 8 quarters (October 2018–September 2020) followed by monthly feedback for 6 months (October 2020-March 2021). The antibiotic prescribing rates were compared between pre and post intervention in 4 diseases in which there was evidence that antibiotic therapy was not required according to the project on rational use of antibiotics including traumatic wound (FTW), respiratory infection (RI), acute diarrhea (AD) and antibiotic prophylaxis in vaginal delivery of normal term labor (APL). The segmented regression analysis of interrupted time series was employed. Results: Feedback to prescribing physician immediately reduced antibiotic prescribing rate in FTW, RI, and AD, and immediately reduced antibiotic expenditure in FTW, RI, AD and APL, but did not reach statistically significant levels. Trend of antibiotic prescribing rate in FTW significantly decreased by 1.89% per quarter (95%CI: -2.72 to -1.07), while that of antibiotic expenditure significantly decreased by 2,935 bath per quarter (95%CI: -4,427 to -1,442). Conclusion: The single intervention of information feedback to individual prescriber reduces physicians’ antibiotic prescribing rate and expenditures in some diseases. Other behavioral economics based measures should be designed and implemented in conjunction with information feedback measures to increase effectiveness in reducing the rate of antibiotic prescribing in hospitals.
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ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
World Health Organization. The world medicines situation. Geneva: World Health Organization; 2004
Chayakul P, Chongtrakul P, Wananukul W, Phunnu phurot P, Karnchanarat P, Yotsombat K, et al. Rational drug use hospital manual. 2nd ed. Nontha- buri: Agricultural Co-Operation Federation of Thai- land; 2015.
Ruangrong J, Theerawattananon Y, Chayketkaew U, Tuntiwet S. Study of interventions and strategies to improve the use of antimicrobials in hospitals in Thailand. Nonthaburi: Health Intervention and Technology Assessment Program; 2009.
Sumpradit N, Anuwong K, Chongtrakul P, Khanab- kaew K, Pumtong S. Outcome of the antibiotics smart use project: a pilot study in Saraburi province Journal of Health Science 2010; 19: 899-911.
Gong CL, Zangwill KM, Hay JW, Meeker D, Doctor JN. Behavioral economics interventions to improve outpatient antibiotic prescribing for acute respiratory infections: a cost-effectiveness analysis. J Gen Intern Med 2018; 34: 846–54.
Burke LE, Styn MA, Sereika SM. Using mHealth technology to enhance self-monitoring for weight loss: a randomized trial. Am J Prev Med 2012; 43: 20–6.
Phaliphot V, Chittiwattanarat K, Ruengorn C, Lucksiri A. Effects of antibiotic restriction program in critical care surgery patients at Maharat nakorn Chaingmai hospital. Thai Pharmaceutical and Health Science Journal 2015; 10: 59-66.
Meeker D, Linder JA, Fox CR, Friedberg MW, Persell SD, Goldstein NJ, et al. Effect of behavioral interventions on inappropriate antibiotics prescribing among primary care practices a randomized clinical trial. JAMA 2016; 315: 562-70.
Kaewpimon P. Health care and quality promotion of vulnerability in multicultural society. Pattani: Faculty of Nursing, Prince of Songkla University; 2016.
Field A. Discovering statistics using SPSS. London: Sage; 2009.
Chaitham A, Chowwanapoonphon H. Development of system for rational antibiotic prescribing: case studies of respiratory infections and simple fresh traumatic wound in a community hospital in upper northern. Thai Journal of Pharmacy Practice 2021; 13: 79-97.
Mohareb AM, Alyssa RL, Sanchez SM, Walensky RP, Hyle EP. Addressing antibiotic overuse in the outpatient setting: Lessons from behavioral economics. Mayo Clinic Proc 2021; 96: 537-42.