Effectiveness and Safety of Sahastara Extract Cream for Knee Pain in Patients with Primary Osteoarthritis: a Pilot Study

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Published: Apr 30, 2020
Keywords:
cream with Sahastara preparation extract osteoarthritis of knee knee pain

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Tapanon Suakittikul
Student of Master of Sciences Program (Applied Thai Traditional Medicine), Faculty of Medicine, Thammasat University
Boonchana Pongcharoen
Department of Orthopedic Surgery, Faculty of Medicine, Thammasat university
Arunporn Itharat
Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani 12120, Thailand 3Center of Excellence on Applied Thai Traditional Medicine Research (CEATMR), Faculty of Medicine, Thammasat University, Klongluang, Pathumthani 12120, Thailand
Srisopa Ruangnoo
Department of Applied Thai Traditional Medicine, Faculty of Medicine , Thammasat University,Klong Neuang, Klong Luang
Puritat Kanokkangsadal
Department of Applied Thai Traditional Medicine, Faculty of Medicine , Thammasat University,Klong Neuang, Klong Luang
Tanyada Lertdamrongdej
Student of Master of Sciences Program (Applied Thai Traditional Medicine), Faculty of Medicine, Thammasat University

Abstract

Objective: To study the tendency of effects from using the cream containing extract from Sahastara preparation (SHT cream) in knee pains among patients with primary knee osteoarthritis (OA). Methods: This study was a quasi-experimental study in 20 knee OA patients. The volunteers received SHT cream for applying to the affected knee area in amount of 2 grams for 3 times a day (morning, afternoon and evening) for 2 weeks.  The study assessed the change before and after applying the cream using Visual Analogue Scale (VAS) for pain, Modified Thai WOMAC Index scores, and duration of walking on a flat surface for 100 meters. The study evaluated safety from history-talking and laboratory tests. Results: Volunteers receiving SHT cream had a significantly lower level of all outcomes. In addition, no side effects and no changes in liver and renal function test were identified. Conclusions:  SHT cream shows a tendency of effect in reducing knee pain and safety. The results of this study can be further expanded to clinical trial phase II for comparing the effectiveness of SHT cream with modern medicine.

Article Details

Issue
Vol. 12 No. 4 (2020): Oct-Dec
Section
Research Articles

        ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์  บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ 

Author Biographies

Tapanon Suakittikul, Student of Master of Sciences Program (Applied Thai Traditional Medicine), Faculty of Medicine, Thammasat University

Department of Applied Thai Traditional Medicine,

Faculty of Medicine, Thammasat University, Pathumthani 12120

Boonchana Pongcharoen, Department of Orthopedic Surgery, Faculty of Medicine, Thammasat university

Department of Orthopedic Surgery,Faculty of Medicine,

Thammasat university, Pathumthani 12120

Srisopa Ruangnoo, Department of Applied Thai Traditional Medicine, Faculty of Medicine , Thammasat University,Klong Neuang, Klong Luang

Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat Universit and Center of Excellence on Applied Thai Traditional Medicine Research, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani, 12120, Thailand

Puritat Kanokkangsadal, Department of Applied Thai Traditional Medicine, Faculty of Medicine , Thammasat University,Klong Neuang, Klong Luang

Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat Universit and Center of Excellence on Applied Thai Traditional Medicine Research, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani, 12120, Thailand.

Tanyada Lertdamrongdej, Student of Master of Sciences Program (Applied Thai Traditional Medicine), Faculty of Medicine, Thammasat University

Department of Applied Thai Traditional Medicine,

Faculty of Medicine, Thammasat University, Pathumthani 12120

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