Effect of Pharmaceutical care with Motivational interview and Education Provided by Pharmacists in Patients with Chronic Obstructive Pulmonary Disease in Cha-uat Hospital
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Abstract
Objective: To study the effect of pharmaceutical care with motivational interview and education provided by pharmacists in patients with chronic obstructive pulmonary disease on lung function, re-admission to the emergency room, re-hospitalization, number of inhalers used to relieve asthma, effects of COPD on well-being and daily activities, medication knowledge, incorrect use of inhalers and medication adherence. Methods: The study was a randomized and controlled trial. Subjects were 134 COPD patients at the Easy Asthma Clinic of Cha-uat Hospital. The subjects were randomly assigned to the experimental group (n = 69) and the control group (n = 65). The experimental group received MI, education on medication and self-care for 2 sessions (at month 2 and 4) and 2 follow-up phone calls (at months 1 and 3). The control group received regular services from the hospital. The patients were followed up 3 times at months 0, 2 and 4. Results: At the end of the study, lung function (P = 0.013), medication adherence (P = 0.001) and medication knowledge (P‹0.001) of the experimental group were significantly higher than those of the control group. Asthma attack (P = 0.003), the number of inhaler use to relieve symptoms (P = 0.021), incorrect use of inhalers (P ‹0.001), and medication non-adherence (P<0.001) of the study group were significantly lower than those of the control group. Re-admission to emergency room, re-hospitalization and impacts of COPD on the well-being and daily activities of the study group were not different from those of the control group. Conclusion: MI and educational provision by pharmacists significantly increased lung function, medication adherence and medication knowledge, and significantly reduced the number of patients with asthma attack, number of inhaler use to relieve symptoms, medication non-adherence, and incorrect use of inhalers.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
World Health Organization. The top 10 causes of death [online]. [cited Nov 29, 2019]. Available from: www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.
National Health Security Office. Public health statistic 2019 [online]. 2019 [cited Nov 19, 2019]. Available from:www.hfocus.org/content/2019/05/17202.2019.
Boonsawat W. Future trend in COPD management. Bangkok: Prachachon; 2011.
DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care 2004;42: 200–9.
Sabaté E, World Health Organization. Noncommu nicable Diseases and Mental Health Cluster. Adherence to long-term therapies: policy for action: meeting report, 4-5 June 2001 [online]. 2001 [cited Nov 30, 2019]; Available from: apps.who.int/iris/han dle/10665/66984
Bender BG, Pedan A, Varasteh LT. Adherence and persistence with fluticasone propionate/salmeterol combination therapy. J Allergy Clin Immunol. 2006; 118: 899–904.
Breekveldt-Postma NS, Gerrits CMJM, Lammers JWJ, Raaijmakers JAM, Herings RMC. Persistence with inhaled corticosteroid therapy in daily practice. Respir Med. 2004; 98: 752–9.
Leiva-Fernández J, Leiva-Fernández F, García-Ruiz A, Prados-Torres D, Barnestein-Fonseca P.Efficacy of a multifactorial intervention on therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled trial. BMC Pulm Med 2014; 14: 70.
Herborg H, Soendergaard B, Froekjaer B, Fonnes baek L, Jorgensen T, Hepler CD, et al. Improving drug therapy for patients with asthma--part 1: Patient outcomes. J Am Pharm Assoc (Wash). 2001; 41:539–50.
Sthapornnanon N. Medication non adherence. Thai Bulletin of Pharmaceutical Sciences. 2012;7:23–39.
Worth H, Dhein Y. Does patient education modify behaviour in the management of COPD? Patient Educ Couns. 2004; 52: 267–70.
Kuwalairat P, Mayases P, Thongdang A. Assess ment of Pharmaceutical care outcome on the patients with chronic obstructive pulmonary disease attending community hospital in Thailand. Isan Journal of Pharmaceutical Sciences. 2014; 10: 80–92.
Khienphet C. Outcome measurement of counseling on patients with Asthma at Taphanhin Crown Prince Hospital [master thesis]. Bangkok: Silpakorn University; 2004.
Miller WR, Rollnick S. Motivational interviewing: Helping people change, 3rd ed. New York, NY: Guilford Press; 2013.
Khdour MR, Hawwa AF, Kidney JC, Smyth BM, McElnay JC. Potential risk factors for medication non-adherence in patients with chronic obstructive pulmonary disease (COPD). Eur J Clin Pharmacol. 2012; 68: 1365–73.
Naderloo H, Vafadar Z, Eslaminejad A, Ebadi A. Effects of motivational interviewing on treatment adherence among patients with chronic obstructive pulmonary disease: a randomized controlled clinical trial. Tanaffos. 2018; 17: 241–9.
Sangpum P, Sthapornnanon N, Poolsup N. Clinical outcomes and health related quality of life of pharmaceutical care prior to physician visit in asthma clinic. Thai Pharmaceutical and Health Science Journal. 2010; 5: 23-30.
Baker DW, DeWalt DA, Schillinger D, Hawk V, Ruo B, Bibbins-Domingo K, et al. “Teach to goal”: theory and design principles of an intervention to improve heart failure self-management skills of patients with low health literacy. J Health Commun. 2011; 16 Suppl 3: 73–88.
Pothirat C, Chaiwong W, Phetsuk N, Liwsridakun C, Bumroongkit C, Deesomchock A, et al. Peak expiratory flow rate as a surrogate for forced expiratory volume in 1 second in COPD severity classification in Thailand. Int J Chron Obstruct Pulmon Dis. 2015; 10: 1213–8.
Jones PW, Harding G, Berry P, Wiklund I, Chen W-H, Kline Leidy N. Development and first validation of the COPD Assessment Test. Eur Respir J. 2009; 34: 648–54.
Claire L, Coralie B, Eric B. The modified Medical Research Council scale for the assessment of dyspnea in daily living in obesity: a pilot study. BMC Pulm Med. 2012; 12: 1-7.
Sriwun S. Effect of pharmaceutical care in uncontrolled hypertensive patients [master thesis]. Songkhla: Prince of Songkla University; 2010.
Jarab AS, Alqudah SG, Khdour M, Shamssain M, Mukattash TL. Impact of pharmaceutical care on health outcomes in patients with COPD. Int J Clin Pharm. 2012; 34: 53–62.
Hämmerlein A, Müller U, Schulz M. Pharmacist-led intervention study to improve inhalation technique in asthma and COPD patients. J Eval Clin Pract. 2011; 17: 61–70.
Areerob S, Anlamlert W. The influence of seamless pharmaceutical care for patient in chronic obstructive pulmonary disease clinic at Phaholpol payahasena Hospital, Kanchanaburi Province. Thai Journal of Pharmacy Practice 2019; 11: 256-67.
