Effects of the Use of Brief Motivational Intervention and Educational Materials by Pharmacist in Patients with Acute Coronary Syndrome during Hospitalization : A Randomized Controlled Trial
Main Article Content
Abstract
Objective: To determine the effects of brief motivational intervention (MI) by pharmacist together with educational materials for patients with acute coronary syndrome (ACS) during hospitalization. Method: The study design was a randomized controlled trial. Subjects were ACS patients admitted to Intensive care unit and medical wards. Patients were allocated using stratified randomization into control group (n=51) and study group (n=51). All patient received counseling from pharmacist for 3 times i.e., on the days of admission, discharge and follow-up visit. The control group received usual counseling from pharmacist while the study group received brief MI by pharmacist and educational materials. Outcomes of the study included hospital readmission after discharge (RAD) within 28 days after discharge, medication adherence, knowledge of disease and drug, and patient satisfaction toward pharmacy counseling. Results: Rate of RAD within 28 days after discharge in study group was significantly lower than that of control group (2% and 21.6% respectively; P=0.006). Medication adherence measured by pills count in the study group was significantly higher more than that of control group (992 and 94.66.8 respectively; P <0.001). Knowledge on disease and drugs in study group was significantly higher than that of control group both at discharge (22.31.2 and 18.72.7 out of the full score of 23, respectively; P<0.001) and follow-up date (22.11.1 and 19.12.9 respectively; P<0.001). Satisfaction toward counseling in the study group were significantly higher than that in the control group (564.1 and 53.26.1 out of the full score of 60, respectively; P=0.01). Conclusion: Brief MI by pharmacist together with educational materials in ACS patients decreases RAD, increases medication adherence, knowledge on disease and drugs and patient satisfaction toward pharmacy counseling.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
2. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Executive summary: heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation 2016; 133: 447–54.
3. World Health Organization. Cardiovascular diseases [online]. 2017. [cited May 19, 2018]. Available from: www.who.int/news-room/fact-sheets/detail/cardiova scular-diseases-(cvds)
4. Department of Disease Control. Theme of heart's day 2017. Non-communicable disease data [online]. 2017. [cited Jun 8, 2018]. Available from: www.thai ncd.com/2016/news/hot-news-etail.php?id=12808& gid=18
5. Department of Disease Control. Amount and death rates per 100,000 persons in ischemic heart dis- ease. Non-communicable disease data [online]. 2016. [cited May 26, 2018]. Available from: www. thaincd.com/information-statistic/non-communicabl e-disease-data.php
6. Hengratsamee K. ST elevation myocardial infarction patient situation in Thailand [online]. 2016. [cited Oct 8, 2016]: Available from www.cdi.thaigov.net/c di/folder_a/folder_f/1aa.pdf
7. Fingar K, Warshington R, Trends in hospital readmis sions for four high-volume conditions, 2009-2013 [online]. 2015. [cited May 19, 2018]. Available from: www.hcup-us.ahrq.gov/reports/statbriefs/sb196-Re admissions-Trends-High-Volume-Conditions.jsp
8. Anukoolsawat P, Sritara P, Teerawattananon Y. Costs of lifetime treatment of acute coronary syndrome at Ramathibodi hospital. Thai Heart Journal 2006; 19: 132–43.
9. McIlvennan CK, Eapen ZJ, Allen LA. Hospital read- missions reduction program. Circulation 2015; 131: 1796–803.
10. Krumholz HM, Lin Z, Drye EE, Desai MM, Han LF, Rapp MT, et al. An administrative claims measure suitable for profiling hospital performance based on 30-day all-cause readmission rates among patients with acute myocardial infarction. Circulation 2011; 4: 243–52.
11. Hansen LO, Young RS, Hinami K, Leung A, Williams MV. Interventions to reduce 30-day rehospitaliza- tion: A systematic review. Ann Intern Med 2011; 155: 520–8.
12. Ravn-Nielsen LV, Duckert M-L, Lund ML, Henriksen JP, Nielsen ML, Eriksen CS, et al. Effect of an in-hospital multifaceted clinical pharmacist intervene tion on the risk of readmission: a randomized clinical trial. JAMA Intern Med 2018; 178: 375–82.
13. Budiman T, Snodgrass K, Chang AK. Evaluation of pharmacist medication education and post-dis charge follow-up in reducing readmissions in patients with ST-Segment Elevation Myocardial Infarction (STEMI). Ann Pharmacother 2015; 50: 118-24.
14. Clark LT, Bellam SV, Shah AH, Feldman JG. Analysis of prehospital delay among inner-city patients with symptoms of myocardial infarction: implications for therapeutic intervention. J Natl Med Assoc 1992; 84: 931–7.
15. Phemphul C, Pinyopasakul W, Asdornwised U, Lak sanabunsong P. The effectiveness of a structured discharge planning program in patients with acute coronary syndrome on functional status, satisfac tion and unexpected hospital revisits. J Nurs Sci 2011; 29: 120-8.
16. Arnold SV, Smolderen KG, Kennedy KF, Li Y, Shore S, Stolker JM, et al. Risk factors for rehospitalI zation for acute coronary syndromes and unplanned revascularization following acute myocardial infarction. J Am Heart Assoc 2015; 4: e001352.
17. Tasakorn V, Sahadsanon D. Sampling and blinding. In: Pitisuttithum P, Picheansoonthon C, editors. Textbook of clinical research [online]. 2011 Avai lable from: www.tm.mahidol.ac.th/th/tropical-medi cine-knowledge/book-clinic/Textbook-of-ClinicalRes earch/145-70.pdf.
18. Scott NW, McPherson GC, Ramsay CR, Campbell MK. The method of minimization for allocation to clinical trials: a review. Control Clinical Trials 2002; 23:662–74.
19. Rungsilp M, Soorapan S, Pongwecharak J, Vongpu warak P. The effects of pharmaceutical care provision on patients with acute coronary syndromes and hypercholesterolemia at Patthalung hospital pharmacy department. Songklanagarind Medical Journal 2008; 26: 261-74.
20. Nuanchuay P. Effect of pharmaceutical care on the control of risk factors for progression of renal function in patients with chronic kidney disease at Thasala hospital [Master Thesis]. Songkla: Prince of Songkla University; 2012.
21. Saengcharoen W, Lerkiatbundit S, Pattharachayakul S. The effect of pharmacist education for know ledge of disease, medication and behavior in acute coronary syndrome patient in Songkhla: Faculty of Pharmacy, Prince of Songkla University; 2010.
22. Detkong T. Motivational interviewing for NCDs. Bangkok: Beyond publishing; 2017.
23. Ramkhamheang Hospital. 100% occlusion of coronary artery heart with treatment [online]. 2012. [cited May 20, 2018]. Available from: www.You tube .com/watch?v=m2T_h3vUojE.
24. Chaimol P. Pharmacist education and pictogram of instruction on drug use for diabetes outpatients in primary care units [master Thesis]. Songkhla: Prince of Songkla University; 2016.
25. Ho PM, Lambert-Kerzner A, Carey EP, Fahdi IE, Bryson CL, Melnyk SD, et al. Multifaceted interven- tion to improve medication adherence and second dary prevention measures after acute coronary syndrome hospital discharge a randomized clinical trial. JAMA Intern Med 2013; 174: 186–93.
26. Strömberg A, Dahlström U, Fridlund B. Computer-based education for patients with chronic heart failure. a randomised controlled multicentre trial of the effects on knowledge, compliance and quality of life. Patient Educ Couns 2006; 64: 128–35.
27. Buckley T, McKinley S, Gallagher R, Dracup K, Moser DK, Aitken LM. The effect of education and counselling on knowledge, attitudes and beliefs about responses to acute myocardial infarction symptoms. Eur J Cardiovasc Nurs 2007;6:105–11.