Efficiency in Ultrafiltration Rate and Electrolyte Values between Hemoconcentrator and Dialyzer by in Vitro Study using Simulating Cardiopulmonary Bypass Model
Efficiency in Ultrafiltration Rate and Electrolyte Values
Keywords:
ultrafiltration, cardiopulmonary bypass, open heart surgeryAbstract
The utility of ultrafiltration in cardiopulmonary bypass (CPB) is a major role to decrease volume overload in cardiac surgery. The objective was to compare ultrafiltration rate and electrolyte values between hemoconcentrator and dialyzer. Twenty-four bags of expired blood from blood blank were diluted with acetar fluid 2,200 mL and added heparin in every experiment. After that, it passed through hemoconcentrator or dialyzer circuit in CPB model flow rate 300 mL/minute. Then, during testing ultrafiltration rate, hematocrit and potassium were measured every 30, 40, and 80 minutes, respectively. The results showed that ultrafiltration rate and hematocrit in hemoconcentrator group increased higher significantly than dialyzer group [766.17 ± 101.87 vs 103.58 ± 32.00 mL/min (p < 0.001) and 17.83 ± 6.91 vs 9.08 ± 1.24 (p = 0.001)], respectively. However, electrolyte levels were not different between groups. In conclusion, hemoconcentrator should be used to decrease volume overload and remove fluid excess in cardiac surgery
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