Cytologic-histologic Correlation of Conventional Pap Smear with LSIL/HPV Change
Cytologic-histologic Correlation of Pap Smear with LSL/HPV Change
Keywords:
Pap smear, Human papilloma virus (HPV), cytologic-histologic correlation, low grade squamous intraepithelial lesion/HPV change, carcinomaAbstract
Cervical cancer is one of the few cancers that can prevent up to 80 percent. This study was a descriptive retrospective study of cytologic-histologic correlation of conventional Pap smear with LSIL/HPV and the incidence of HPV infection. The subjects were retrieved from 16,611 archival conventional Pap smear slides in the Department of Anatomical Pathology, Buddhachinaraj Phitsanulok Hospital between 2016 October 1 to 2019 September 30. Sixty cases diagnosed as LSIL/HPV were included in the study and correlated with the histologic results. The incidence of HPV infection was 0.4 percent and commonly presented in the age range of 30-50 years old with average age of 41.56 years. Eleven cases were excluded from the study due to no histology reports. The results showed normal results (24.5%), LSIL/HPV change (46.9%) HSIL (24.5%) and carcinoma (4.1%). LSIL/HPV change screening was 46.9 percent of the likelihood of a biopsy, with a confidence range between 33.7 and 60.6 percent. In conclusion, conventional Pap smear is also an appropriate way to screen for cervical cancer because it is easy, safe and cheap, useful for prevention and surveillance to reduce the number of new cancer patients and reduce the death rate from cervical cancer
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