Comparison of INR Control between Patients Attending Warfarin Clinic and Those in General Clinic of Sisaket Hospital
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Abstract
Objective: To compare anticoagulation control and the incidence of adverse events between patients in the warfarin clinic and those in general clinics in Sisaket Hospital. Methods: This research was a prospective study in 143 outpatients treated with warfarin at a special cardiology clinic in internal medicine department and 143 of those in general clinics, attending the hospital between August 1 and October 31, 2018. The subjects were selected by systematic random sampling with a ratio of 1: 1. All patients were followed-up for 3 visits. The researcher provided pharmaceutical care to the patients and clinical data were collected. Results: There was no statistically significant difference in time with anticoagulation control in therapeutic range between two groups of subjects (54.85 and 50.20%, respectively; P=0.43). Although time in therapeutic range of patients in the warfarin clinic was higher than that of patients in general clinic. Pharmacists in the warfarin clinic identified 41 adverse events from warfarin with the rate of 0.69 person-years. While only 7 adverse events (0.11 person-years) in general clinics were identified. Patients can use the drug more accurately. The incidence of adverse drug reactions in 1 patient or mild bleeding was found, but no serious adverse reactions were found. Conclusion: The involvement of pharmacists in warfarin clinic enables more detection of warfarin-related problems. The results of this study may lead to the expansion of outpatient pharmacy care networks of the department of neurology in Sisaket Hospital.
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ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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