Effect of Pharmaceutical Care on Drug Therapy-Related Quality of Life in Cancer Patients Receiving Chemotherapy: A Randomized Controlled Trial
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Abstract
Objectives: To determine drug therapy-related quality of life in cancer patients receiving pharmaceutical care compared to those receiving usual. Method: This study was a single-blinded randomized controlled trial in cancer patients receiving chemotherapy at Samutprakarn Hospital. The study compared the groups receiving pharmaceutical care by providing knowledge and counseling on disease/drug/adverse drug reactions and self-care practice of patients receiving chemotherapy, identifying and resolving drug-related problems, with the control group receiving usual care of the Hospital. The primary outcome was drug therapy-related quality of life as measured by the Patient-Reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL) before and after the provision of pharmaceutical care for both groups. Changes of quality of life of both groups were compared using independent sample t-test. The study was conducted during November 2020–February 2021. Results: Differences in drug therapy-related quality of life scores assessed by the PROMPT-QoL between the first and second measurement in study group were higher than those in the control group in all dimensions of the scale (P<0.01). Overall scores improved by 17.48±9.43 and 3.08±5.90 in the study and control groups, respectively, which differed statistically (P<0.001). Conclusion: Pharmaceutical care provision increased drug therapy-related quality of life among cancer patients receiving chemotherapy more than usual care did. Therefore, such service should be encouraged for cancer patients receiving chemotherapy.
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ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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