Determining Factors in Self-medication with Non-prescribed Antibiotics: A Preliminary Qualitative Study in Cambodian Pharmacy Students based on the Theory of Planned Behavior

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Huykhim UNG
Tipaporn Kanjanarach

Abstract

Objectives: To explore Cambodian pharmacy students’ behavior in relation to self-medication with non-prescribed antibiotics and to adopt the Theory of Planned Behavior (TPB) to elicit determining factors, i.e., their attitudes toward using non-prescribed antibiotics for self-medication, perceived subjective norm of self-medication with antibiotics and perceived behavioral control of self-medication without antibiotics. Method: This was a qualitative study. Twenty pharmacy students year 3 to year 5 from the Faculty of Pharmacy of one university in Cambodia were interviewed online. Data analysis was conducted using content analysis. Result: Sixteen participants used antibiotics for self-medication. The symptoms that they self-treated with antibiotics were sore throat (n=6), diarrhea (n=5), cough (n=3), flu (n=6), infected wound (n=2) and severe acne (n=2). The common sources of antibiotics were from pharmacies and existing supplies at home. Most participants indicated that using antibiotics was beneficial as it saved time and money and helped the symptoms to be cured quickly. However, few participants were of the view that using antibiotics could cause antibiotic resistance. Family members and close friends were their main references in self-medication practice. Most of their reference group self-medicated with antibiotics and suggested that they do so. However, most participants did not feel pressured to follow their reference’s suggestions. They were confident that they can control themselves not to self-medicate with antibiotics if they felt that was preferable. The findings from this study also suggested a hypothesis that, in Cambodian pharmacy students, their positive attitudes toward using antibiotics for self-medication may discourage them from practicing self-medication without antibiotics; subjective norm may not have influence on their practice, where their perceived behavioral control may encourage them to self-medicate without antibiotics. Conclusion: In the next study, we suggest conducting a quantitative study to test this proposed hypothesis. In addition, the findings of this qualitative study elicited useful themes that can be used to develop a scale to measure each component of the TPB for the next quantitative study.

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References

Al Essa M, Alshehri A, Alzahrani M, Bustami R, Adnan S, Alkeraidees A, et al. Practices, awareness and attitudes toward self-medication of analgesics among health sciences students in Riyadh, Saudi Arabia. Saudi Pharm J 2019; 27: 235-9.

Zafar SN, Syed R, Waqar S, Zubairi AJ, Vaqar T, Shaikh M, et al. Self-medication amongst university students of Karachi: Prevalence, knowledge and attitudes. J Pak Med Assoc 2008; 58: 214-7.

Jairoun A, Hassan N, Ali A, Jairoun O, Shahwan M, Hassali M. University student’s knowledge, attitudes , and practice regarding antibiotic use and asso- ciated factors: a cross-sectional study in the United Arab Emirate. Int J Gen Med 2019; 12: 235-46.

Widayati A, Suryawati S, de Crespigny C, Hiller JE. Self-medication with antibiotics in Yogyakarta City Indonesia: a cross-sectional population-based survey. BMC Res Notes 2011; 4: 491. doi: 10.1186/ 1756-0500-4-491.

Al-Azzam SI, AI-Husein BA, Alzoubi F, Masadeh MM, Al-Horani Ma. Self-medication with antibiotics in Jordanian population. Int J Occup Med Environ Health 2007; 20: 373-80.

Sihavong A, Lundborg CS, Syhakhang L, Akkha vong K, Tomson G, Wahlstrom R. Antimicrobial self- medication for reproductive tract infections in two provinces in Lao People’s Democratic Republic. Sex Transm Infect 2006; 82: 182-6

Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf 2014; 5: 229-41.

Klemenc-Ketis Z, Hladnik Z, Kersnik J. Self-medica tion among health care and non-healthcare students at University of Ljubljana, Slovenia. Med Princ Pract 2010; 19: 395-401.

Virmani S, Nandigam M, Kapoor B, Makhija P, Nair S. Antibiotic use among health science students in an Indian university: A cross sectional study. Clin Epidemiology Glob Health 2017; 5: 176-9.

Karen G, Barbara K, Rimer, Viswanath K. Health behavior and health education: Theory, research, and practice. 4th ed. San Francisco: Jossey-Bass; 2008

Wang L, Wang L. Using theory of planned behavior to predict the physical activity of children: Probing gender differences. BioMed Res Int 2015; 2015: 536904.

Hayden J. Introduction to health behavior theory. 2nd ed. Burlington, MA: Jones & Bartlett Learning; 2013.

Chhorvoin O, Frances D, Erika V, James CM, Mary-Louise M. Pervasive antibiotic misuse in the Cambodian community: antibiotic-seeking behaviour with unrestricted access. Antimicrob Resist Infect Control 2017; 6: 30. doi: 10.1186/s13756-017-0187-y.

Thomas ANR, Sidonn K, Thyl M, Nicola T, Joanne L, Sreng B, et al. Antimicrobial resistance in Cambodia: a review. Int J Infect Dis 2019; 85: 98-107.

Sovanthida S, Sonia R, Sothavireak B, Sophea C, Socheata P, Chantra P, et al. Invisible medicine sellers and their use of antibiotics: a qualitative study in Cambodia. BMJ Glob Health 2019; 4: e001787. doi: 10.1136/bmjgh-2019-001787.

Pineles LL, Parente R. Using the theory of planned behavior to predict self-medication with over-the-counter analgesics. J Health Psychol 2013; 8: 1540-9.

Karimy M, Rezaee-Momtaz M, Tavousi M, Monta zeri A, Araban M. Risk factors associated with self-medication among women in Iran. BMC Public Health 2019; 19: 1033. doi: 10.1186/s12889-019-730 2-3.

Silva da MGC, Soares MC, Muccillo-Baisch AL. Self-medication in university students from the city of Rio Grande, Brazil. BMC Public Health 2012; 12: 339. doi: 10.1186/1471-2458-12-339.

Widayati A, Suryawati S, de Crespigny C, Hiller JE. Beliefs about the use of non-prescribed antibiotics among people in Yogyakarta city, Indonesia: a qualitative study based on the theory of planned behavior. Asia Pac J Public Health 2015; 27: 402-13.

Niwandinda F, Lukyamuzi EJ, Ainebyona C, Sse bunya VN, Murungi G, Atukunda EC. Patterns and practices of self-medication among students enrolled at Mbarara University of Science and Techonology in Uganda. Integr Pharm Res Pract 2020; 9: 41-8.

Elmahi OKO, Musa RAE, Shareef AAH, Omer MEA, Elmahi MAM, Mohamed RIH, et al. Perception and practice of self-medication with antibiotics among medical students in Sudanese Universities: a Cross-sectional study [online]. 2021 [cited Feb 9, 2021]. Available from: assets.researchsquare.com/fil es/rs-260575/v1/c23664be-aa65-4851-95cb-de4cce59a744.pdf.

DeVellis RF. Scale development theory and applications. 4th ed. Los Angeles: SAGE. 2017