Effects of Counseling and Monitoring of Adverse Drug Events (ADE) in Patients with Breast and Colorectal Cancer Receiving Chemotherapy in Nangrong Hospital

Abstract

Objective: To study the outcomes of counseling on chemotherapy and monitoring of adverse drug events (ADEs) in patients with breast and colorectal cancer receiving chemotherapy in Nangrong hospitals. Method: This research was a pre-post test study in one group of subjects. The samples were 27 breast cancer patients and 19 colorectal cancer patients receiving chemotherapy from Nangrong Hospital. The intervention was counseling by pharmacists. The studies assessed the outcomes pre and post counseling using the chemotherapy knowledge test and the self-care behavior test for patients receiving chemotherapy. The study assessed ADEs using the Common Terminology Criteria for Adverse Criteria. Events (CTCAE) and the Naranjo's Algorithm. Results: Patients with breast and colorectal cancer, both new and old ones, had significantly increased knowledge and self-care behaviors after counseling. The most common ADE in breast cancer patients was hair loss, while that in patients with colorectal cancer was exhaustion. The majority of ADEs in both types of cancer patients was mild to severe (98.80% and 100%, respectively). The relationship between ADEs and drug was probably in 88.75% and 80.00% in breast cancer patients, and patients with colorectal cancer, respectively. Conclusion: The pharmacy counseling on chemotherapy in cancer patients receiving chemotherapy enables them to have better knowledge on chemotherapy, self-care behavior and ADEs of chemotherapy. Therefore, the study encourages pharmacy counseling as conducted in the study.