Clinical Inertia in Type2 Diabetic Patients in Community Hospitals in Ubon Ratchathani

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ลิขิต ผลดี
พิสิษฐ์ เวชกามา
น้องเล็ก คุณวราดิศัย
แสวง วัชระธนกิจ

Abstract

Objectives: To measure time from treatment initiation to clinical inertia in patients with type2 diabetes treated with oral antidiabetic agents identified by comparing with the Clinical Practice Guideline of Diabetes and to identify factors associated with clinical inertia.  Methods: This retrospective cohort study used electronic medical records of newly diagnosed type 2 diabetes patients who received medical services in 16 community hospitals in Ubon Ratchathani from June 1, 2008 through December 31, 2015.  The primary data were fasting blood sugar and types of oral antidiabetic agents received on the day of hospital visits, which were examined to identify diabetic patients with clinical inertia. Those with clinical inertia were the patients receiving no treatment intensification when the treatment goal was not achieved according to Clinical Practice Guidelines for Diabetes in 2008, 2011 and 2014, Identification of factors associated with clinical inertia was conducted using logistic regression analysis. Results: Of 15,228 eligible patients, 5,903 (38.76%) patients had clinical inertia.  The average time to first clinical inertia in patients receiving medical services during June 1, 2008 through December 31, 2010 (phase 1), January 1, 2011 through December 31, 2013 (phase 2) and January 1, 2014 through December 31, 2015 (phase 3) were 377.7 ± 5.46, 348.75 ± 3.39 and 316.75 ± 3.62 days respectively.  The proportion of patients with at least one clinical inertia was 19.35%, 32.61% and 42.73% in phase 1 to phase 3 respectively.  Statistically significant factors associated with lower clinical inertia were patients aged 55 – 62 years (OR = 0.75; 95%CI = 0.60 –0.94), and aged≥63 years (OR = 0.67; 95%CI = 0.54 – 0.83), being female (OR = 0.84; 95%CI = 0.73 – 0.98), patients with hypertension (OR = 0.85; 95%CI = 0.59 – 0.81), patients receiving medical service at two hospitals (OR = 0.14; 95%CI = 0.04 – 0.50, OR = 0.52; 95%CI = 0.35 – 0.79).  Conclusion: Clinical inertia was observed more frequently and with shorter time from phase 1 to phase 3.  Approximately one third of type 2 diabetic patients had clinical inertia.  Patients with older age, being female, having hypertension, and receiving care from 2 community hospitals were less likely to have clinical inertia than the others.

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References

1. International Diabetes Federation. IDF diabetes atlas 6th ed. [online]. 2013 [cited Jul 27, 2015]. Available from: www.idf.org/e-library/epidemiology-research/diabetes-atlas.html.

2. Bureau of Health Policy and Strategy. Public health statistic. Nonthaburi: Ministry of Public Health; 2013

3. Khoury JC, Kleindorfer D, Alwell K, Moomaw CJ, Woo D, Adeoye O, et al. Diabetes mellitus: a risk factor for ischemic stroke in a large bi-racial population. Stroke 2013; 44: 1500-4.

4. Ratanasan C. Impact of diabetes in Thailand [online]. 2014 [cited Dec 16, 2015]. Available from: i-regist.igenco.co.th/web/dmthai_old/news_and_kno wledge/371.

5. Potisat S, Krairittichai U, Jongsareejit A, Sattaputh C, Arunratanachote W. A 4-year prospective study on long-term complications of type 2 diabetic patients: the Thai DMS diabetes complications (dd.comp.) project. J Med Assoc Thai 2013; 96: 637-43.

6. World Health Organization. About diabetes [online]. 2014 [cited Jul 27, 2015]. Available from: www. who.int/diabetes/en/.

7. Diabetes Association of Thailand, The Endocrine Society of Thailand, Department of Medical Services, National Health Security Office. Clinical practice guideline for diabetes 2011. Bangkok: Srimuang printing; 2011.

8. O’Connor PJ, Sperl-Hillen JM, Johnson PE, Rush WA, Biltz G. Clinical inertia and outpatient medical errors. J Med Licens Discip 2008; 94: 19-29.

9. Rangsin R, Tasanawiwat P, MedResNet group. An assessment on quality of care among patients diagnosed with type 2 diabetes and hypertension visiting ministry of public health and Bangkok metropolitan administration hospitals in Thailand, 2012 [online]. 2014 [cited Aug 8, 2015]. Available from: www.thaincd.com/2016/mission/documents-de tail.php?id=12363&tid=&gid=1-027.

10. Aujoulat I, Jacquemin P, Rietzschel E, Scheen A, Trefois P, Wens J, et al. Factors associated with clinical inertia: an integrative review. Adv Med Educ Pract 2014; 5: 141-7.

11. Lin J, Zhou S, Wei W, Pan C, Lingohr-Smith M, Levin P. Does clinical inertia vary by personalized A1C goal? a study of predictors and prevalence of clinical inertia in a US manage care setting. Endocr Pract 2016; 22: 151-61.

12. Yu S, Schwab P, Bian B, Radican L, Tuncell K. Use of add-on treatment to metformin monotherapy for patients with type 2 diabetes and suboptimal glycemic control: a U.S. database study. J Manag Care Spec Pharm 2016; 22: 272-80.

13. Rajpathak SN, Rajgopalan S, Engel SS. Impact of time to treatment intensification on glycemic goal attainment among patients with type 2 diabetes failing metformin monotherapy. J Diabetes Compli cations 2014; 28: 831-5.

14. McEwen LN, Bilik D, Johnson SL, Halter JB, Karter AJ, Mangione CM, et al. Predictors and impact of intensification of antihyperglycemic therapy in type 2 diabetes. Diabetes Care 2009; 32: 971-6.

15. Lang VB, Markovic BB, Kranjcevic K. Family physician clinical inertia in glycemic control among patients with type 2 diabetes. Med Sci Monit 2015; 21: 403-11.

16. Khunti K, Wolden ML, Thorsted BL, Anderson M, Davies MJ. Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 people. Diabetes Care 2013; 36: 3411-7.

17. Diabetes Association of Thailand, The Endocrine Society of Thailand, Department of Medical Service, Health, National Health Security Office. Clinical practice guideline for diabetes 2008. Bangkok: Rungsin printing 1977; 2008.

18. Diabetes Association of Thailand, The Endocrine Society of Thailand, Department of Medical Service, National Health Security Office. Clinical practice guideline for diabetes 2014. Bangkok: Aroon printing; 2014.