Medication Errors and Adverse Drug Events in Patients Receiving Antineoplastic Agents
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Abstract
Objective: To study types, frequency, and the severity of medication errors (MEs) and to identify the relationship between MEs and adverse drug events (ADEs) in patients receiving chemotherapy. Methods: The study was a cross-sectional descriptive study conducted by collecting the data from 137 pre-printed prescriptions for patients receiving chemotherapy. Additionally, practice of pharmacists in chemotherapy preparation, nurses in patient wards and the occurences of ADEs during treatment were observed. Results: Most patients were diagnosed with breast cancer (n=71, 51.8%). Majority of subjects were admitted to obstetrics and gynecology ward (n=67, 48.9%). The regimen received by the majority of patients was FOLFOX-4 (n=64, 46.7%). The study identified 406 MEs. The most prevalent MEs were administration errors (n=325, 80.05%), dispensing errors (n=74, 18.23%) and prescribing errors (n=7, 1.72%). The most common ADEs were alopecia (n=95, 62.0%), anorexia (n=75, 54.7%) and nausea (n=74, 54.0%). Data analysis showed no correlation between MEs and ADEs. Conclusion: Most MEs occurred during drug administration. The improvement of drug administration systems and enhancement of knowledge as well as skills of practitioners could decrease MEs.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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