Designing the System for Management of Unused Medicine in Patients with Diabetes Mellitus by Using Root Cause Analysis Framework

Main Article Content

วิภาดา ปุณณภาไพศาล
ภัทรินทร์ กิตติบุญญาคุณ
กฤษณี สระมุณี

Abstract

Objective: The purposes of this study were 1) to investigate number of items, quantity and cost of unused medicines as well as their predictive factors, 2) to analyze root causes of unused medicines, and 3) to design system for management of unused medicine by health care team. Method: The concepts of root cause analysis were used to design three phases of the study including both quantitative and qualitative studies. Phase I was a survey exploring number of items, quantity and cost of unused medicines in 403 diabetic patients. Phase II was a semi-structured interview with 19 patients having the highest number of items of unused medicines and health professionals including one family doctor, one general practitioner, 4 pharmacists and 4 nurses. Finally, phase 3 involved the presentation of the information from phases 1 and 2 to health professional teams, and then applied the concepts of root cause analysis to the problem of unused medicines. Result: The majority of participants being survey on unused medicine was female (73.40 %) with the total cost of unused medicines of 64,119.54 Baht or 159.11 Baht per person on average. Unused medicine with the highest quantity was metformin 500 mg, followed by aspirin 81 mg, glipizide 5 mg, enalapril 5 mg and simvastatin 20 mg, respectively. Metformin 500 mg was unused medicines with the highest cost followed by mixtard 70/30 (vial), hydralazine 25 mg, losartan 50 mg and simvastatin 20 mg, respectively. Predicting factors of having more than 4 items of unused medicines were age 60 years and over (ORadj 0.58, 95%CI 0.36-0.95) and having income of 1,000-5,000 Baht per month (ORadj 0.52, 95%CI 0.32-0.85). Contributing factors for the unused medicines included patient factor (attitude, belief, knowledge of disease and medication, and medication-taking behaviors), system of health care services and other factors (such as a lack of caregivers and community participation). Health team adjusted the roles of doctors, nurses and pharmacists to address the problems of unused medicines and arranged home health care services in diabetic patients. Conclusion: The collaborations within health care team and involvement of patients, family members and community could help develop the system to address the problems of unused medicines effectively and sustainably.

Article Details

Section
Research Articles

References

1. American Diabetes Association. Standards of medical care in diabetes 2015. Diabetes Care. 2015;38:37-49.

2. Champoonot P, Suwannaprom P, Chowwanapoonpohn H. Leftover drugs and drug behavior of people in Chiang Mai province. Thai Pharmaceutical and Health Science Journal. 2011;6:105-11.

3. Pisutthikosan C. Prevalence and factors related to leftover medicine in patients with type 2 diabetes mellitus at Prachasamosorn community medicine unit, Khonkaen province [master thesis]. Khonkaen: Khonkaen University; 2014.

4. Nimsai W. Amount, price and causes of diabetic drugs returned by diabetic patients at Bangkhla Hospital, Chachoengsao Provice. Journal of Phrapokklao Nursing College 2009;21:23-31.

5. Mackridge AJ. Medicines non-use in primary care [dissertation]. Birmingham: University of Aston; 2005.

6. Jaroenpan J, Tansakul C. Health behavior. 6th ed. Mahasa- rakham: Klungnanwitthaya; 2007.

7. Becker MH. The health belief model and sick role behavior. Health Educ Monogr 1974;2:409-19.

8. Sota J. Applications of concepts and theories to develop health behavior. Khonkaen: Khonkaen university; 2014.

9. The National Patient Safety Agency, National Health Services. Root cause analysis toolkit [online]. 2009 [cited May 5, 2017]. Available from: www.npsa.nhs.uk/health/re sources/root_cause_analysis.

10. Kittboonyakun P. Improving the management of chronic pain: using root cause analysis to inform a strategy for pharmaceutical care [dissertation]. Aberdeen: University of Aberdeen; 2010.

11. Cochran WG, Cox GM. Experimental designs. 2nd ed. New York: John Wiley and Sons; 1957.

12. Braund R, Gn G, Matthews R. Investigating unused medications in New Zealand. Pharm World Sci. 2009; 31: 664-9.

13. Kengganpanich T, Leerapan P, Kengganpanich M, Nunthasen K, Lattanand K. Factors related to herbal consumption for controlling blood sugar of patients with type 2 diabetes mellitus. Journal of Boromarajonani College of Nursing 2015; 31:13-25.

14. Suwannaprom P, Niamhun N, Champoonot P, Phosupa C, Chowwanapoonpohn H, Supakul S, et al. Items and value of household leftover medicine for chronic conditions at Sansai-Luang sub-district, Sansai district, Chiang Mai province. Thai Pharmaceutical and Health Science Journal. 2012;7:22-8.

15. Chaiyakunapruk N, Nimpitakpong P, Jeanpeerapong N, Dilokthornsakul P. A study of the size and impact of drug possession exceeding necessary policy recommendations and solutions. Phitsanulok: Naresuan University; 2012.

16. Sirithanawutichai T, Wongsauwasup A, Nopthuan W, Krueanak T. The effectiveness of village health volunteers in Muang district, Mahasarakham province making visits to the homes of diabetes mellitus patients. Journal of Science and Technology Mahasarakham University. 2013;29:439-45.

17. Tunpichart S. Effectiveness of pharmacist home health care for type 2 diabetes in Bangkok metropolitan: A community base study [dissertation]. Chulalongkorn: University of Chulalongkorn; 2011.

18. World Health Organization. Guidelines for medicine dona- tions [online]. 2011 [cited Jun 7, 2017]. Available from: apps.who.int/iris/bitstream/10665/44647/1/9789241501989_eng.pdf.