Properties of Self-prepared Nasal Saline Irrigation
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Abstract
Objective: To assess properties of self-prepared nasal saline irrigation (SPNSI). Methods: Prepare SPNSI at the concentrations of 0.9% and 1.8% by mixing various types of salt including Prung Tip® (PT), TESCO® (TC), BigC® (BC), TIPP SALT® (KT), and pharmaceutical grade salt (PG) into various types of water including reverse osmosis (RO), drinking water in sealed containers (DW), and boiled tap water (BTW). Properties of SPNSI assessed in the study included clarity and color, odor, pH, and sterility right after prepared and after stored at room temperature (RT) for 7 days. Results: All formulations of SPNSI were clear, colorless and odorless. The pH of freshly prepared SPNSI can be classified into 2 groups including weak base (pH = 7.02-8.12) when prepared from DW or BTW, and weak acid (pH = 6.09-6.70) when prepared from RO water. The sterility test showed that SPNSI prepared by mixing DW with Prung Tip food grade salt or PG could be kept at RT for 1 and 7 days without bacterial growing, respectively. Conclusion: All SPNSIs were clear, colorless and odorless. The pH and sterility properties of each SPNSI were different depending on types of water and salt used. Properties of SPNSI prepared by mixing PG or Prung Tip food grade salt into DW for freshly prepared to use within 1 day were acceptable in laboratory tests. However, there’s need for the study on safety and efficacy of SPNSI in patients.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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