Effect of Pharmaceutical Care on Drug Therapy-Related Quality of Life in Outpatients
Article Sidebar
Main Article Content
Abstract
Objective: To study drug therapy-related quality of life in outpatients receiving pharmaceutical care compared to those who didn’t. Methods: A randomized controlled trial conducted in 414 outpatients at Bangkok Metropolitan Administration General Hospital (Klang Hospital) during March 2016 to October 2016. The subjects were randomly allocated into group with usual care and study group. Drug therapy-related quality of life was measured by the Patient-reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL) with 43 items covering 9 dimensions. The researchers collected the data twice i.e., before intervention and after intervention during next patient visit to the hospital. Results: Pharmaceutical care group scored significantly higher in the following domains of drug therapy-related quality of life than usual care group--domain 2 Medication and Disease Information from Physicians, Pharmacists or Nurses (P<0.001), domain 3 Satisfaction to Medication Effectiveness (P<0.05), domain 5 Psychological Impacts of Medication Use (P<0.001) and the total score (P<0.001). Conclusions: Pharmaceutical care service provided by pharmacist plays an important role in improving drug therapy-related quality of life among patients. The PROMPT-QoL is a standardized measure applicable for the evaluation of patients’ drug therapy-related quality of life.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
2. American Pharmacists A, National Association of Chain Drug Stores F. Medication therapy manage-ment in pharmacy practice: core elements of an MTM service model (version 2.0). J Am Pharm Assoc 2008 ; 48:341-53.
3. Hepler CD, Strand LM. Opportunities and responsibilities in pharmaceutical care. Am J Hosp Pharm 1990;47:533-43.
4. Cipolle RJ, Strand LM, Morley PC. Pharmaceutical care practice: the patient-centered approach to medication management services. 3rd ed. New York: McGraw-Hill; 2012.
5. Singhal PK, Raisch DW, Gupchup GV. The impact of pharmaceutical services in community and ambu-latory care settings: evidence and recommendations for future research. Ann Pharmacother 1999;33:1336-55.
6. Cheng Y, Raisch DW, Borrego ME, Gupchup GV. Economic, clinical, and humanistic outcomes (ECHOs) of pharmaceutical care services for minority patients: a literature review. Res Social Adm Pharm 2013; 9:311-29.
7. Sakthong P, Suksanga P, Sakulbumrungsil R, Winit-Watjana W. Development of Patient-reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL): A novel instrument for medication management. Res Social Adm Pharm 2015;11:315-38.
8. Kheir NM, Mil JWFv, Shaw JP, Sheridan JL. Health-related quality of life measurement in pharma-ceutical care targeting an outcome that matters. Pharm World Sci 2004;26:125-8.
9. Greenhalgh J, Long AF, Flynn R. The use of patient reported outcome measures in routine clinical practice: lack of impact or lack of theory? Soc Sci Med 2005; 60:833-43.
10. Valderas JM, Kotzeva A, Espallargues M, Guyatt G, Ferrans CE, Halyard MY, et al. The impact of measuring patient-reported outcomes in clinical practice: a systematic review of the literature. Qual Life Res 2008;17:179-93.
11. Viswanathan M, Kahwati LC, Golin CE, Blalock SJ, Coker-Schwimmer E, Posey R, et al. Medication therapy management interventions in outpatient settings: a systematic review and meta-analysis. JAMA Intern Med 2015;175:76-87.
12. Mohammed MA, Moles RJ, Chen TF. Impact of pharmaceutical care interventions on health-related quality-of-life outcomes: A systematic review and meta-analysis. Ann Pharmacother 2016;50:862-81.
13. Murawski MM, Bentley JP. Pharmaceutical therapy-related quality of life: conceptual develop- ment. J Soc Adm Pharm 2001;18:2-14.
14. Ernst ME, Iyer SS, Doucette WR. Drug-related problems and quality of life in arthritis and low back pain sufferers. Value Health 2003;6:51-8.
15. Renberg T, Lindblad AK, Tully MP. Testing the validity of a translated pharmaceutical therapy-related quality of life instrument, using qualitative 'think aloud' methodology. J Clin Pharm Ther 2008;33:279-87.
16. Krska J, Morecroft CW, Poole H, Rowe PH. A novel instrument to measure medicines-related quality of life. Int J Clin Pharm 2013;35:488.
17. Krska J, Morecroft CW, Rowe PH, Poole H. Measuring the impact of long-term medicines use from the patient perspective. Int J Clin Pharm 2014; 36:675-8.
18. Nontapat Sonsa-ardjit. Psychometric properties of the Patient-reported Outcome Measure of Pharma-ceutical Therapy: Quality of Life (PROMPT-QoL) at King Chulalongkorn Memorial hospital [dissertation]. Bangkok: Chulalongkorn University; 2014.
19. Pattarin Sukarnjanaset. Psychometric properties of the Patient-reported Outcome Measure of Pharma-ceutical Therapy: Quality of Life (PROMPT-QoL) at Ramathibodi hospital [dissertation]. Bangkok: Chulalongkorn University; 2014.
20. Wipaporn Munpan. Psychometric properties of the Patient-reported Outcome Measure of Pharmaceutical Therapy: Quality of Life (PROMPT-QoL) at Phramong kutklao hospital [dissertation].Bangkok: Chulalongkorn University; 2014.
21. Athipat Cleesuntorn. Education in Thailand and the challenging issues [online]. 2016 [cited Jan 8, 2017]. Available from: www.en.moe.go.th/index.php? option=com_content&view=article&id=3660:education-in-thailand-and-the-challenging-ssues&catid=23:article.
22. Faul F, Erdfelder E, Buchner A, Lang AG. Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods 2009; 41:1149-60.
23. Cohen J. Quantitative methods in psychology; a power primer. Psychol Bull 1992;112: 155-9.
24. Cohen HJ. Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum; 1988.
25. Crawford SD, Couper MP, Lamias MJ. Web surveys: perceptions of burden. Soc Sci Comput Rev 2001;19:146-62.
26. Bernsten C, Bjorkman I, Caramona M, Crealey G, Frokjaer B, Grundberger E, et al. Improving the well-being of elderly patients via community pharmacy-based provision of pharmaceutical care. Drugs Aging 2001;18:63-77.
27. Butt M, Mhd Ali A, Bakry MM, Mustafa N. Impact of a pharmacist led diabetes mellitus intervention on HbA1c, medication adherence and quality of life: A randomised controlled study. Saudi Pharm J 2016; 24 : 40-8.
28. Clifford RM, Batty KT, Davis TME, Davis W, Stein G, Stewart G, et al. A randomised controlled trial of a pharmaceutical care programme in high-risk diabetic patients in an outpatient clinic. Int J Pharm Pract 2002; 10:85-9.
29. Cohen LB, Taveira TH, Khatana SA, Dooley AG, Pirraglia PA, Wu WC. Pharmacist-led shared medical appointments for multiple cardiovascular risk reduction in patients with type 2 diabetes. Diabetes Educ 2011;37:801-12.
30. Hanlon JT, Weinberger M, Samsa GP, Schmader KE, Uttech KM, Lewis IK, et al. A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly out-patients with polypharmacy. Am J Med 1996; 100: 428-37.
31. Jaeschke R, Singer J, Guyatt GH. Measurement of health status: ascertaining the minimal clinically important difference. Control Clin Trials 1989; 10: 407-15.
32. Crosby RD, Kolotkin RL, Williams GR. Defining clinically meaningful change in health-related quality of life. J Clin Epidemiol 2003; 56: 395-407.
