Effects of Pharmaceutical Care Based on the Clinical Practice Guideline of Migraine in a University Pharmacy: a Pilot Study

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ปรางทิพย์ ล้อดงบัง
รณิดา เดชะ
วัลยา สุนทรา
สุดา นันกลาง
รจเรศ หาญรินทร์
สายทิพย์ สุทธิรักษา

Abstract

Objective: To compare treatment outcomes between patients with migraine receiving pharmaceutical care based on clinical practice guideline of migraine and those receiving usual medical treatment from pharmacy. Methods: A randomized controlled trial was carried out between January 1 and March 31, 2011. A total of 46 patients were randomly allocated into 2 groups, i.e., those receiving pharmaceutical care based on the clinical practice guideline of migraine (a treatment group, n=23) and those receiving usual medical treatment from a pharmacy (control group, n=23). The researchers measured severity of headache pain, frequency of headache attacks and health status and overall happiness for two months. Results: The treatment group and the control showed no difference in severity of headache pain and frequency of headache attacks at day 1, week 4 and 8 (p>0.05). However, social and spiritual health, and overall happiness at week 4 and 8 in the treatment group were significantly higher than those in the control group (p<0.05). Moreover, mental health in the treatment group was higher than that in the control group (p<0.05). Conclusion: Pharmaceutical care based on a clinical practice guideline of migraine does not improve headache pain and frequency of headache attack including physical health in patients with migraine when compared with a usual medical treatment of a pharmacy. However, it improves social, spiritual, and mental health including overall happiness in patients with migraine

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