Potentially Inappropriate Medication Usage by Nursing Home Residents
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Abstract
Objective: To determine medication usage and potentially inappropriate medications (PIMs) of nursing home residents. Method: The study was a cross-sectional descriptive research with the collection of data on medication use from health registries, interview and examination of medications being used by the elderly with age≥60 years, receiving at least one medication, and residing at Ban Bang Khae Welfare Development Center for Older Persons, Bangkok. The researchers used the 2012 AGS Beers criteria for evaluation of PIMs. Results: A total of 105 elderly residents were recruited with 75.2% being female, an average age of 79.1 ± 7.7 years, and presenting with hypertension (60%), bone and joint disease (41%) and hyperlipidemia (40%). About 86% of them used a minimum of 5 medications (polypharmacy). Three most frequently used medications were cardiovascular drugs (23.8%), vitamins and electrolytes (20.1) and drugs for central nervous system (14.5%). Sixty one percent of elderlies received PIMs. The 3 most common PIMs used were chlorpheniramine (17.4%), orphenadrine (15.9%) and lorazepam (14.5%). Number of drug items was significantly associated with the increased likelihood of receiving PIMs (p<0.01). A binary logistic regression indicated that receiving ≥ 11 drug items was associated with 11.34 times increase of the likelihood of receiving PIMs (95% CI=1.97-65.33), compared to those with 0-4 drug items. Sex, age, education, number of diseases/syndromes and number of drug sources were not associated with PIMs receiving. Conclusions: The elderlies residing at the residential home used multiple medications and therefore are at risk of using PIMs. Our findings highlight the needs for higher vigilances to optimize drug safety among nursing home residents.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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