Factors Affecting Medication Adherence of Diabetic Patients at Police General Hospital
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Abstract
Objective: To determine the prevalence of medication non-adherence in diabetic patients at Police General Hospital and to study the factors affecting medication adherence. Methods: This cross-sectional descriptive study collected the data from medical records and patient interview on the factors hypothesized as predictors of medication adherence. The researchers also measured medication adherence using questionnaires. The study was conducted at the endocrine clinic, Police General Hospital. Results: Total of 168 diabetic patients had an average medication adherence score of 37.4±2.2 (total score=40). The prevalence of medication non-adherence was 16.7% (28 patients). The number of co-morbid conditions had a negative relationship with the medication adherence (r=-0.179, P = 0.020). The patients who were unskilled labors/bus drivers/taxi drivers had a lower level of medication adherence score than the other occupations (P = 0.035). Multiple regression analysis revealed 3 factors affecting medication adherence were working as unskilled labors/bus drivers/taxi drivers (P = 0.018), being housewife/house husband/retired (P = 0.030) and the number of co-morbid conditions (P = 0.003) Conclusion: Majority of patients had good medication adherence. The patients who had many co-morbid conditions and those working as unskilled labors/bus drivers/taxi drivers had a significantly lower level of medication adherence than the other groups. These 2 groups of patients need a close attention and intervention if medication non-adherence is identified.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
2. Institue of Medical Research and Technology Assessment. Situation of diabtes/hypertension and their complications in Thailand. Bangkok: Ministry of Public Health; 2013.
3. Lydon D. Psychosocial factors impacting on treatment adherence in diabetes. Student psychology journal.1:171-87.
4. Clark M. Adherence to treatment in patients with type 2 diabetes. J Diabetes Nurs. 2004;8:386-91.
5. Teklay G, Hussien J, Tesfaye D. Non-adherence and associated factors among type 2 diabetic patients at jimma university specialized hospital, southwest Ethiopia. J Med Sci. 2013 1; 578-84.
6. Thapa B, Pokharel PK, Poudel IS, Sharma SK, Shyangwa PM, Sangraula H, et al. Factors affecting on adherence to the prescribed drugs in diabetic patients visiting a tertiary care centre. Journal of nobel medical college. 2013;2: 11-7.
7. Kumar P. A study on medication non-adherence in ambulatory diabetic patients and need for pharmacist intervention for improving patient adherence. Indian journal of research in pharmacy and biotechnology. 2013;1:446-7.
8. Ho PM, Rumsfeld JS, Masoudi FA, McClure DL, Plomondon ME, Steiner JF, et al. Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med 2006;166:1836-41.
9. Ahmad NS, Ramli A, Islahudin F, Paraidathathu T. Medication adherence in patients with type 2 diabetes mellitus treated at primary health clinics in Malaysia. Patient Prefer Adherence 2013; 7: 525-30.
10. Mann DM, Ponieman D, Leventhal H, Halm EA. Predictors of adherence to diabetes medications: the role of disease and medication beliefs. J Behav Med 2009;32:278-84.
11. Adisa R, Alutundu MB, Fakeye TO. Factors contributing to nonadherence to oral hypoglycemic medications among ambulatory type 2 diabetes patients in Southwestern Nigeria. Pharmacy Practice. 2009;7:163-9.
12. Shams ME, Barakat EA. Measuring the rate of therapeutic adherence among outpatients with T2DM in Egypt. Saudi Pharm J. 2010;18: 225-32.
13. Park KA, Kim JG, Kim BW, Kam S, Kim KY, Ha SW, et al. Factors that affect medication adherence in elderly patients with diabetes mellitus. Korean Diabetes J. 2010;34:55-65.
14. Chaiman P. Factors associated with regular use of medications among type 2 diabetic patients at Kumuang, Burirum. [master thesis]. Bangkok: Mahidol University; 2009.
15. Budphakdee B. Medication compliance among diabetic patients received care from mobile health unit of Phutong health promoting district hospital in 2013. [online]. 2013 [cited 2013 Nov 4]. Available from: http://203.157.165.4/ssko_presents/filepre sents/3330501343786-8-1481.doc.
16. Wannapinyo A. Development and validation of an instrument to assess general knowledge and attitudes of patients with diabetes. [master thesis]. Bangkok: Chulalongkorn University; 2002.
17. Depression center, Prasrimahapho hospital. 9-items Depression scale (9Q). [online]. 2013 [cited 2014 Apr 15]. Available from: http://www.thaidep ression.com/www/56/298Q.pdf.
18. Lam PW, Lum CM, Leung MF. Drug non-adherence and associated risk factors among Chinese geriatric patients in Hong Kong. Hong Kong Med J. 2007;13:284-92.
19. Johnson M, Griffiths R, Piper M, Langdon R. Risk factors for an untoward medication event among elders in community-based nursing caseloads in Australia. Public Health Nurs. 2005;22:36-44.
20. Sthapornnanon N. Medication non adherence. Thai Bulletin of Pharmaceutical Sciences. 2012; 7: 1-17.
21. Srisawang A. Factors influencing adherence to antidepressants in Thai depressed patients[master thesis]. Bangkok: Chulalongkorn University; 2007.
22. Sujipittham T. Adherence assessment and factors affecting adherence to art among HIV-infected /AIDS at Taksin hospital. [master thesis]. Bangkok: Chulalongkorn University; 2010.
23. Kanchanarak O. Factors predicting medication adherence behavior of schizophrenic patients in community. [master thesis]. Bangkok: Chulalongkorn University; 2002.
24. Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens 2008;10:348-54.
25. Manakitjongkol W. Use of the medication regimen complexity index (MRCI) to assess diabetic outpatient adherence at Saraburi hospital. [master thesis]. Bangkok: Chulalongkorn University; 2006.
26. Tiv M, Viel J-F, Mauny F, Eschwège E, Weill A, Fournier C, et al. Medication adherence in type 2 diabetes: The ENTRED study 2007, a French Population-Based Study. PLoS ONE. 2012;7: e32412.
27. Srisuwan N. Health behaviors for prediction blood glucose level of diabetic patients admitted at Samutprakarn hospital. [master thesis]. Bangkok: Chulalongkorn University; 2007.
28. Lohavisavapanich R. Impact of education and counseling provided by a clinical pharmacist on diabetic outpatients at King Chulalongkorn Memorial Hospital. [master thesis]. Bangkok: Chulalongkorn University; 2003.
29. Kalyango JN, Owino E, Nambuya AP. Non-adherence to diabetes treatment at Mulago Hospital in Uganda: prevalence and associated factors. Afr Health Sci. 2008;8:67-73.
30. Bezie Y, Molina M, Hernandez N, Batista R, Niang S, Huet D. Therapeutic compliance: a prospective analysis of various factors involved in the adherence rate in type 2 diabetes. Diabetes Metab. 2006;32: 611-6.
31. Kalsekar ID, Madhavan SS, Amonkar MM, Makela EH, Scott VG, Douglas SM, et al. Depression in patients with type 2 diabetes: impact on adherence to oral hypoglycemic agents. Ann Pharmacother. 2006;40: 605-11.
32. Donnan PT, MacDonald TM, Morris AD. Adherence to prescribed oral hypoglycaemic medication in a population of patients with Type 2 diabetes: a retrospective cohort study. Diabet Med. 2002;19:279-84.
33. Wabe NT, Angamo MT, Hussein S. Medication adherence in diabetes mellitus and self management practices among type-2 diabetics in Ethiopia. N Am J Med Sci. 2011;3:418-23.
