Effects on Pregnant Women and Newborns from COVID-19 Infection among Pregnant Women Infected Prior to or During Delivery
Effects on Pregnant women and Newborns from COVID-19 Infection
Keywords:
COVID-19 outbreak, infection during delivery, the coronavirus 2019, pregnant womenAbstract
Pregnant women and newborns are at risk of the coronavirus (SARS-CoV-2). This research aimed to investigate the impact of COVID-19 on pregnant women and newborns by comparing the clinical outcomes of those infected before childbirth to those infected while giving birth. This retrospective study was conducted on 139 pregnant women diagnosed with RT-PCR/ATK or both, including all infants born to these pregnant women in the Phetchabun Hospital from January 2020 to July 2022. Of 139 cases, 92 were infected before childbirth, and 47 were infected during delivery. Women with the infection during childbirth had a mean age of 25.06 years, more than half were asymptomatic and received less vaccinated. Women infected while giving birth also developed more obstetric complications, pneumonia and received more favipiravir than others. Neonates to pregnant women with the infection during delivery were more premature and had significantly longer hospital stays and higher fevers than the newborns to prior delivery infected women. In conclusion, more complications occurred among pregnant women (and infants) who had COVID-19 at delivery than before delivery. These findings can be helpful to monitor and take care of pregnant women and newborns infected during delivery
References
Bs M, Bs M. COVID-19: an insight into SARS-CoV-2 pandemic originated at Wuhan City in Hubei Province of China [Internet]. 2020 Jul 18 [cited 2022 Sep 3]. Available from: https://clinmedjournals.org/articles/jide/journal-of-infectious-diseases-and-epidemiology-jide-6-146.php?jid=jide
WHO Director-General’s opening remarks at the media briefing on COVID-19 [Internet]. 2020 March 11 [cited 2022 Apr 8]. Available from: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020
Coronavirus disease (COVID-19) World Health Organization [Internet]. 2019 [cited 2022 Apr 8]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019
Struyf T, Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MM, et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19. Cochrane Database Syst Rev 2021;2021(2):CD013665.
Kumari A, Anand S, Vidyarthi A. Effects of COVID-19 during pregnancy on maternal and neonatal outcome: a retrospective observational study in tertiary teaching hospital, India. J Fam Med Prim Care 2022;11(5):1820–5.
Department of Obstetrics and Gynecology, Faculty of Medicine. Chiang Mai University. Physiological changes in pregnant women [Internet]. 2015 [cited 2022 Sep 3]. Available from: https://w1.med.cmu.ac.th/obgyn/lecturestopics/medical-student-5/3657/
Dashe JS, Bloom SL, Spong CY, Hoffman BL. Williams obstetrics, 25th ed. New York City, New York, USA: McGraw Hill Professional; 2018.
Karaçam Z, Kizilca-Çakaloz D, Güneş-Öztürk G, Çoban A. Maternal and perinatal outcomes of pregnancy associated with COVID-19: systematic review and meta-analysis. Eur J Midwifery 2022;6:42. doi: 10.18332/ejm/149485
Khorsukworakul C, Khobkhun J, Anusornteerakul S, Harnklar S. COVID-19 infectious disease: a guideline for caring of pregnant women during the epidemic. J Nurs Health Res 2021;22(2):138–49.
Nana M, Hodson K, Lucas N, Camporota L, Knight M, Nelson-Piercy C. Diagnosis and management of covid-19 in pregnancy. BMJ 2022;377:e069739. doi: 10.1136/bmj-2021-069739
Royal College of Obstetricians and Gynecologists of Thailand. Medical practice guidelines of the Royal College of Obstetricians and Gynecologists of Thailand on the care of pregnant women infected with COVID-19. revised edition Version 6 [Internet]. 2021 Aug 20 [cited 2022 Dec 21]. Available from: http://thg-health.com/covid19/94-covid-21.html
Department of Health, Ministry of Public Health. Pregnant woman care after birth and newborns under the situation of the epidemic of COVID-19 [Internet]. 2021 [cited 2022 Dec 21]. Available from: https://covid19.anamai.moph.go.th/web-upload/2xdccaaf3d7f6ae30ba6ae1459eaf3dd66/m_document/6734/34104/file_download/621df7052185dce54911a781c52527cb.pdf
Jafari M, Pormohammad A, Sheikh Neshin SA, Ghorbani S, Bose D, Alimohammadi S, et al. Clinical characteristics and outcomes of pregnant women with COVID-19 and comparison with control patients: A systematic review and meta-analysis. Rev Med Virol 2021;31(5):1–16.
Rasmussen S, Jamieson D. Coronavirus disease 2019 and pregnancy is déjà vu all over again. BJOG Int J Obstet Gynaecol 2022;129(2):188–91.
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