Epidemiology and Clinicopathological Characteristics of Biopsy-proven Glomerular Disease in Children
Epidemiology and Clinicopathology of Glomerular Disease in Children
Keywords:
epidemiology, clinicopathological characteristics, children, renal biopsyAbstract
A renal biopsy helps to obtain an accurate diagnosis, provides guidance for treatment, indicates the progression of the disease, and offers a prognosis. This study aimed to examine the epidemiology of pediatric glomerular disease patients undergoing renal biopsy, including indications for biopsy, pathological diagnoses, and complications with complete medical records. In this retrospective study includes 165 patients and 169 native renal biopsies performed between July 2010 and December 2024. Their median age was 11 years 7 months (range 6 months-17 years) and females predominated (53.3%). The most common indication of renal biopsy was rapid progressive glomerulonephritis (33.7%). Post infectious glomerulonephritis and lupus nephritis were most frequent pathological diagnoses (29.6%). No complications were found in 83.4%. The most prevalent complication was gross hematuria (13%).The study show rapid progressive glomerulonephritis is most common indication of renal biopsy and post infectious glomerulonephritis is common and significant disease in Thailand
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