The Effectiveness of Modified Coronary Risk Chart (mCRC) and Thai CV Risk Score for Cardiovascular Risk Evaluation in Thai Population
Cardiovascular Risk Evaluation in the Thai Population
Keywords:
Cardiovascular Risk Assessment, Modified Coronary Risk Chart, Thai CV Risk Score, Sensitivity, SpecificityAbstract
Thailand has developed two cardiovascular risk assessment tools: Modified Coronary Risk Chart (mCRC) and Thai CV Risk Score. Despite both being developed specifically for Thai populations, studies comparing their effectiveness show conflicting results. This cross-sectional and retrospective study compared both tools by examining 240 acute myocardial infarction patients aged 35-65 years from 2020-2024 against 240 controls at Phichit Hospital. Results showed Thai CV Risk Score had high specificity of 64.2% but low sensitivity of 54.2%, with positive predictive value of 60.2%, negative predictive value of 58.3%, and overall accuracy of 59.2%. Conversely, mCRC demonstrated high sensitivity of 95.8% but low specificity of 12.9%, with positive predictive value of 52.4%, negative predictive value of 75.6%, and overall accuracy of 54.4%. The tools showed poor agreement (Kappa = 0.088, 95%CI: 0.044-0.132), with mCRC tending to assess risk higher than Thai CV Risk Score. This study concludes that mCRC is suitable for initial screening, while Thai CV Risk Score is appropriate for risk confirmation. Using both tools together may enhance cardiovascular risk assessment effectiveness in the Thai population
References
World Health Organization. Cardiovascular diseases (CVDs) [Internet]. 2021 [cited 2024 Dec 10]. Available from: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)
National Statistical Office. The 2021 cause of death statistics [Internet]. 2023 [cited 2024 Dec 10]. Available from: https://www.nso.go.th/public/e-book/Analytical-Reports/Report_Gender_2023/60/
Srimahachota S, Boonyaratavej S, Kanjanavanit R, Sritara P, Krittayaphong R, Kunjara-Na-Ayudhya R, et al. Thai Registry in Acute Coronary Syndrome (TRACS)-An Extension of Thai Acute Coronary Syndrome Registry (TACS) Group: Lower In-Hospital but Still High Mortality at One-Year. J Med Assoc Thai. 2020;103(4):301-11.
Jitnarin N, Kosulwat V, Rojroongwasinkul N, Boonpraderm A, Haddock CK, Poston WSC. Prevalence of overweight and obesity in Thai population: Results of the National Thai Food Consumption Survey. Eat Weight Disord. 2011;16(4):e242-9.
Laurier D, Nguyen PC, Cazelles B, Segond P, André JM, Rouffet J, et al. Estimation of CHD risk in a French working population using a modified Framingham model. J Clin Epidemiol. 1994;47:1353-64.
Hense HW, Schulte H, Lowel H, Assmann G, Keil U. Framingham risk function overestimates risk of coronary heart disease in men and women from Germany-result from the MONICA Augsburg and the PROCAM cohorts. Eur Heart J. 2003;24:937-45.
Barzi F, Patel A, Gu D, Sritara P, Lam TH, Rodgers A, et al. Cardiovascular risk prediction tools for populations in Asia. J Epidemiol Community Health. 2007;61:115-21.
Hippisley-Cox J, Coupland C, Brindle P. Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study. BMJ. 2017;357:j2099.
D'Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743-53.
De Backer G, Ambrosioni E, Borch-Johnsen K, Brotons C, Cifkova R, Dallongeville J, et al. European guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2003;24(17):1601-10.
Conroy RM, Pyörälä K, Fitzgerald AP, Sans S, Menotti A, De Backer G, et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J. 2003;24(11):987-1003.
Goff DC, Lloyd-Jones DM, Bennett G, Coady S, D'Agostino RB, Gibbons R, et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk. J Am Coll Cardiol. 2014;63(25 Part B):2935-59.
Veerakul G, Khajornyai A, Wongkasia S, Tanomsup S, Tatsanavivat P, Veerakul K, et al. Predicting and preventing cardiovascular events in asymptomatic patients: A 10-year prospective study. Bangkok Med J. 2017;13:1-12.
Sritara P, Cheepudomwit S, Chapman N, Woodward M, Kositchaiwat C, Tunlayadechanont S, et al. Twelve-year changes in vascular risk factors and their associations with mortality in a cohort of 3499 Thais: the Electricity Generating Authority of Thailand Study. Int J Epidemiol. 2003;32(3):461-8.
Vathesatogkit P, Woodward M, Tanomsup S, Ratanachaiwong W, Vanavanan S, Yamwong S, et al. Cohort profile: the electricity generating authority of Thailand study. Int J Epidemiol. 2012;41(2):359-65.
Sukontasarn A, Chaiwong W, Thepsen K, Chomsang P, Samranthin M, Suwanjutah T, et al. Comparison of Cardiovascular Risk Estimation Tools in Thai Hospital Employees. Bangkok Med J. 2021;17(2):93-99.
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