Packed Red Cell Transfusion Volume during Cardiopulmonary Bypass with or without Conventional Ultrafiltration in Adult Cardiac Surgery
Packed Red Cell Transfusion Volume in Adult Cardiac Surgery
Keywords:
Conventional ultrafiltration, Packed red cell, Adult cardiac surgeryAbstract
Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) is intended to remove excess water and increase hematocrit. Packed red cell transfusion has been associated with increased morbidity and mortality following cardiac surgery. The purpose of this study is to compare the volume of packed red cell transfusion during CPB with and without CUF in adult cardiac surgery. The study was conducted on 280 adult patients who had undergone heart surgery, divided into 140 who used the CUB plus CPB and 140 who used CPB only. The results for the group that underwent CPB with CUF showed a mean filtration volume of 1,574.46 ± 961.45 ml. The group that underwent CPB with CUF had a significantly higher volume of packed red cell transfusion than the group that underwent CPB alone, with statistical significance (3.31 ± 0.15 units vs. 2.60 ± 0.14 units, p < 0.001). In summary, CUF during CPB did not lead to a reduction in packed red cell transfusion. However, conventional hemofiltration can be safely used to reduce fluid accumulation and increase hemoglobin levels
References
World Health Organization. Cardiovascular diseases [internet]. 2018 [cited 2018 Oct 1]. Available from: URL: http://www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)
Ministry of Public Health, Bureau of Non-Communicable Diseases. NCDs Annual Report 2017 [Internet]. 2018 [cited 2018 Oct 1]. Available from: URL: http://www.thaincd.com/document/file /download/paper-manual/NCDReport60.pdf
Glenn G, Richard D, Alfred S, Ross U. Cardiopulmonary bypass and mechanical support: Principles & Practice. 4th ed. Philadelphia, Pennsylvania State, USA: Wolters Kluwer; 2016.
Soliman R, Fouad E, Belghith M, Abdelmageed T. Conventional hemofiltration during cardiopulmonary bypass increases the serum lactate level in adult cardiac surgery. Ann Card Anaesth 2016;19(1):45-51.
Yang JC, Sun Y, Xu CX, Dang QL, Li L, Xu YG, et al. Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study. Exp Ther Med 2015;9(1):137-42.
Vlot EA, Verwijmeren L, van de Garde EMW, Kloppenburg GTL, van Dongen EPA, Noordzij PG. Intra-operative red blood cell transfusion and mortality after cardiac surgery. BMC Anesthesiol 2019;19(1):1-7.
Leyh RG, Bartels C, Joubert-Hübner E, Bechtel JF, Sievers HH. Influence of modified ultrafiltration on coagulation, fibrinolysis and blood loss in adult cardiac surgery. Eur J Cardiothorac Surg 2001;19(2):145-51.
Manning MW, Li YJ, Linder D, Haney JC, Wu YH, Podgoreanu MV, et al. Conventional ultrafiltration during elective cardiac surgery and postoperative acute kidney injury. J Cardiothorac Vasc Anesth 2021;35(5):1310-8.
Mongero LB, Tesdahl EA, Stammers A, Weinstein S. The influence of ultrafiltration on red blood cell transfusion during cardiopulmonary bypass. Perfusion 2019;34(4):303-9.
Mongero L, Stammers A, Tesdahl E, Stasko A, Weinstein S. The effect of ultrafiltration on end-cardiopulmonary bypass hematocrit during cardiac surgery. Perfusion 2018;33(5):367-74.
Depboylu BC, Yazman S, Harmandar B. Use of conventional ultrafiltration in patients with pulmonary hypertensive Mitral valve disease undergoing valve surgery. Cardiol Cardiovasc Res 2018;2(2):23-8.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Buddhchinaraj Phisanulok Hospital
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
