Complications and Clinical Outcomes in Peritoneal Dialysis Pediatric Patients

Peritoneal Dialysis Pediatric Patients

Authors

  • Natthida Pongwilairat Department of Pediatric, Buddhachinaraj Phitsanulok Hospital, Phitsanulok

Keywords:

complications, outcomes, peritoneal dialysis, pediatric

Abstract

Peritoneal dialysis (PD) is the preferred dialysis modality for end stage renal disease (ESRD) children. The study aimed to clarify complications and outcomes in peritoneal dialysis  pediatric patients. In this retrospective study, 35 patients  aged less than 15 years old who were treated with  peritoneal dialysis during the period from 1 January 2010 to 31 December 2020. Thirty-five patients had peritoneal  dialysis performed for 876 months. Their median age was 11 years 1 month (range 6 months-15 years). There were 50 episodes of peritonitis in 19 patients (1episode/17.5  patient-months). Time from onset of dialysis to first onset of peritonitis were 1-82 months. Gram negative bacteria  was the most frequent causative organism (42%). Catheter displacement was the most frequent non-infectious complication (50%). Case fatality rate was 22.9%. In conclusion, peritonitis remains a common complication of peritoneal dialysis pediatric patients and Acinetobacter baumannii is the most common causative organism. 

 

References

Schnaper HW. Pathophysiology of progressive renal disease in children. In: Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL, editors. Pediatric nephrology. 7th ed. Berlin Heidelberg, Germany: Springer-Verlag; 2016. p. 2171-206.

Greenbaum LA, Schaefer F. The decision to initiate dialysis in a pediatric patient. In: Warady BA, Schaefer F, Alexander SR, editors. Pediatric dialysis. 2nd ed. New York City, New York State, USA: Springer; 2012. p. 85-100.

Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet 2015;385 (9981):1975-82.

Li PK, Chow KM, Van de Luijtgaarden MW, Johnson DW, Jager KJ, Mehrotra R, et al. Changes in the worldwide epidemiology of peritoneal dialysis. Nat Rev Nephrol 2017;13(2):90-103.

Verrina E, Schmitt CP. Peritoneal dialysis in children. In: Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL, editors. Pediatric nephrology. 7th ed. Berlin Heidelberg, Germany: Springer- Verlag;2016. p. 2381-432.

Szeto CC, Li PK, Johnson DW, Bernardini J, Dong J, Figueiredo AE, et al. ISPD catheter-related infection recommendations:2017 update. Perit Dial Int 2017;37(2):141-54.

LaPlant MB, Saltzman DA, Segura BJ, Acton RD, Feltis BA, Hess DJ. Peritoneal dialysis catheter placement, outcomes and complications. Pediatr Surg Int 2018;34(11):1239-44.

Swartz SJ, Neu A, Mason AS, Richardson T, Rodean J, Lawlor J, et al. Exit site and tunnel infections in children on chronic peritoneal dialysis: findings from the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) Collaborative. Pediatr Nephrol 2018;33(6):1029-35.

Kim JE, Park SJ, Oh JY, Kim JH, Lee JS, Kim PK, et al. Noninfectious complications of peritoneal dialysis in Korean children:A 26-year single-center study. Yonsei Med J 2015;56(5):1359-64.

North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). 2011 Annual Report [online]. 2011 [cited 30 Mar 2022]. Available from: https://naprtcs.org/system/files/2011_Annual_ Dialysis_Report.pdf

Verrina E, Perfumo F, Calevo MG, Rinaldi S, Sorino P, Andreetta B, et al. The Italian pediatric chronic peritoneal dialysis registry. Perit Dial Int 1999;19(2):479-83.

Hoshii S, Wada N, Honda M. Japanese Study Group of Pediatric Peritoneal Dialysis. A survey of peritonitis and exit-site and/or tunnel infections in Japanese children on PD. Pediatr Nephrol 2006;21(6):828-34.

Nakwan N, Dissaneewate P, Lim A, Vachvanichsanong P. Peritoneal dialysisrelated peritonitis in southern Thailand. Int J Artif Organs 2008;31(1):49-54.

Wisanuyotin S, Lertchanaruengrith P, Jiravuttipong A. Peritonitis in children receiving continuous ambulatory peritoneal dialysis in northeast Thailand. J Med Assoc Thai 2011;94(7):789-93.

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Published

2022-05-23