Effectiveness between 5% Cocaine and 10% Lidocaine with 0.025% Oxymetazoline in Nasal Endoscopy Patients
Effectiveness between 5% Cocaine and 10% Lidocaine with 0.025% Oxymetazoline
Keywords:
anesthetics, cocaine, lidocaine, oxymetazoline, nasal endoscopyAbstract
Nasal endoscopy is commonly performed in rhinologic examination. Patients are typically administered a topical anesthetic and decongestant prior to this procedure to alleviate discomfort and improve visualization. The aim of this prospective double-blind randomized controlled trial was to evaluate effectiveness comparison between 5% cocaine and 10% lidocaine with 0.025% oxymetazoline in nasal endoscopy. The 66 sample of patients with indications for nasal endoscopy who were examined at the Otolaryngology Department, Buddhachinaraj Phitsanulok Hospital were enrolled. The results showed that, both of 5% cocaine and 10% lidocaine with 0.025% oxymetazoline, the median of pain during anesthesia (p = 0.356) at endoscopy (p = 0.307) and clarity of endoscopic view (p = 0.408) were not different. The complications from endoscopy were different (p = 0.045), but the number of patients who were satisfied in choosing drug in next visit were not different (p = 0.325). In conclusion, the effectiveness of 5% cocaine was not different from 10% lidocaine with 0.025% oxymetazoline in patients with nasal endoscopy, but 10% lidocaine with 0.025% oxymetazoline may cause the patient to have more burning sensation in the area that is numbing. Therefore, it is an alternative to prepare the patient before endoscopy in the future.
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