The Safety of Intracameral Moxifloxacin Injection for Endophthalmitis Prophylaxis after Phacoemulsification

Intracameral Moxifloxacin Injection for Endophthalmitis Prophylaxis

Authors

  • Chidchanok Rungrattanaubol Department of Ophthalmology, Buddhachinaraj Phitsanulok Hospital, Phitsanulok

Keywords:

endophthalmitis, intracameral injection, moxifloxacin, phacoemulsification

Abstract

Acute endophthalmitis after cataract surgery is rare but results in severe permanent visual loss. There are many studies on the efficiency of intracameral 0.5% moxifloxacin to post-cataract surgery endophthalmitis prophylaxis. The aim of this study was to evaluate the safety of undiluted intracameral 0.5% moxifloxacin for endophthalmitis prophylaxis after phacoemulsification. This study was a prospective randomized controlled clinical trial by studying data between June, 2019 and December, 2019. Ninety patients, 100 eyes were randomized into two groups, 50 eyes were treated with intracameral 0.5% moxifloxacin (500 mug/0.1 ml) after phacoemulsification and 50 eyes were undergone phacoemulsification without intracameral injection. Best corrected visual acuity, intraocular pressure, central corneal thickness, endothelial cell counts and central macular thickness were evaluated preoperatively and for six weeks postoperatively. There were not statistically significant in baseline preoperatively characteristics between two groups including age, sex, site, BCVA, IOP, CCT, endothelial cell counts and CMT. At six weeks postoperatively, there were not statistically significant in BCVA, IOP, CCT, endothelial cell counts and CMT. There were no toxic anterior segment syndrome and endophthalmitis occurred. In conclusion, the intracameral of 0.5% moxifloxacinis safe to be used through the final step after phacoemulsification

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Published

2021-08-29