The outcomes of using anti-AMR guideline to prevent the spread of Drug-resistant Organisms Infections

Abstract

Introduction: Antimicrobial resistance (AMR) is a serious problem in hospitals around the world because it has a high prevalence and tends to increase continuously. Treatment of patients with drug-resistant infections is difficult. Multiple medications cause patients to stay longer in the hospital leading to a higher expense on antimicrobial therapies and a higher mortality rate.

Methods: This retrospective descriptive research aimed to study the results of the provision of anti-AMR guidelines in AMR patients. Two hundred and thirty-two (232) samples were selected through purposive sampling.  Data were medical records of AMR patients admitted  in In –Patients Department, Singburi Hospital, from 1 January -31December 2021.

Results:  The samples were 232 cases: community-acquired infections (46.55%) and nosocomial infections (53.44%). 73.70% had an average age of 66.23 years (SD 14.01) and had co-morbidities. 57.33% had been admitted.  69.39% had drug-resistant experience. 56.02% were internal medicine patients. Most of the samples (58.62%) were found to have urinary tract infections. The most common infection was Escherichia coli (37.93%), followed by respiratory tract infections. The most common strain was Acinetobacter baumannii (32.33%). 47.41 % of the samples received more than one antibiotic. The average expense on antibiotics per case was 11,799.12. baht (SD 1141.70). 30.17% had a length of stay between 16-30 days, and 42.67 % of the samples died of septic shock.

Conclusion: The result revealed that most drug-resistant infections in hospitals were found in general medicine and intensive care units, especially in the elderly with co-morbidities, a history of hospitalization, and drug-resistant infections. It was also found in those who had been performed by catheters/devices in the body. The majority of infection was urinary tract infections, and Escherichia coli was the most common.