Outcome of pharmacoinvasive strategy in patients with ST-segment elevation myocardial infarction in Singburi hospital
Keywords:
Pharmacoinvasive strategy, ST-segment elevation myocardial infarction (STEMI), Total ischemic timeAbstract
Introduction: ST-segment elevation myocardial infarction (STEMI) is a leading cause of death in Thailand. In 2019, STEMI was the third cause of death in Singburi Hospital. This study aimed to investigate the outcome and associated factors of the successful therapy of the pharmacoinvasive strategy in patients with STEMI.
Methods: A retrospective descriptive study was conducted in 163 patients who were hospitalized at Singburi Hospital from 2017 to 2021. Baseline characteristics were reviewed from the medical record. Data were analyzed using frequency, percentage, mean, and standard deviation. Multiple logistic regression analysis was performed to find the correlation between associated factors and the outcome of the treatment. A significant level of 0.05 was used for all analyses and 95% confidence intervals were carried out.
Results: The mean age was 60 years old,. 72.4 % of the patients were males, and the mean door-to-ECG time was 8 minutes. The mean door-to-drug time was 70 minutes. The mean total ischemic time was 325 minutes. The reperfusion therapy was successful in 125 patients (76.7%).
The result of the multiple logistic regression analysis revealed that the statistical significance between associated factors and the successful reperfusion therapy was the total ischemic time of less than 180 mins while associated factors of the failed fibrinolysis therapy was fasting blood sugar (FBS) > 126 mg/dl.
Conclusion: The pharmacoinvasive strategy employed at Singburi Hospital had a success rate of 76.7%, especially when the total ischemic time was less than 180 minutes.
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