Risk factors of suboptimal bowel preparation in elective colonoscopy in Banmi Hospital, Lopburi Province
Keywords:
Colonoscopy, Sodium phosphate for bowel preparation, Suboptimal bowel preparation, Inadequate bowel preparationAbstract
Introduction: Colonoscopy is a gold-standard for colorectal cancer diagnosis. Optimal bowel preparation is the most important factor of successful and good quality colonoscopy. There are many previous studies about the risk factors of suboptimal quality bowel preparation, but most of them did not use sodium phosphate for bowel preparation.
Methods: This retrospective cross-sectional study investigated patients who received sodium phosphate solution for bowel preparation before elective colonoscopy from January 2020 to February 2022. The study recruited 121 patients with suboptimal bowel preparation as a case group and 251 patients with optimal bowel preparation as a control group (a ratio of 1:2). Multiple logistic regression analysis was carried out to identify risk factors associated with suboptimal quality of bowel preparation in patients who received sodium phosphate for bowel preparation before elective colonoscopy.
Results: The result of multiple logistic regression analysis revealed that risk factors statistically significant for suboptimal bowel preparation included the age of 70-79 years (aOR =2.82, 95%CI 1.29-6.13, p=.009), the age of more than 80years (aOR =7.06, 95%CI 2.53-19.65, p<.001), diabetes (aOR =3.28, 95%CI 1.66-6.49, p=.001), active smoking (aOR =4.83, 95%CI 1.57-14.86, p=.006), constipation or bowel habit change symptoms (aOR =5.35, 95%CI 2.94-9.72, p<.001), the history of suboptimal bowel preparation (aOR =7.48, 95%CI 1.26-44.23, p=.02), and ASA more than 3 (aOR =2.97, 95%CI 1.23-7.20, p=.02). However, there were no statistically significant difference in male sex, age of 60-69years, underweight and overweight BMI, inpatient, after 1PM colonoscopy and previous abdominal surgery.
Conclusions: Risk factors that were statistically significant for suboptimal bowel preparation included the age of more than 70 years, diabetes, active smoking, constipation or bowel habit change symptoms, the history of suboptimal bowel preparation, and ASA of more than 3.
*aOR = adjusted odds ratio
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