ความสัมพันธ์ระหว่างลักษณะเซลล์มะเร็งกับการรอดชีพของผู่ป่วยมะเร็งไทรอยด์ที่ได้รับการรักษาในโรงพยาบาลเลย จังหวัดเลย ระหว่างปี พ.ศ. 2560–2565

Abstract

ABSTRACT

Thyroid cancer is the most common endocrine cancer worldwide and in Thailand. There has been no study of survival rate in Loei province. Objective to comparison of type of Thyroid cancer and survival rate after diagnosed in Loei hospital, Loei province. The retrospective cohort study was used. Data were retrieved from Loei hospital-based cancer registry between 1 January 2017 and 31 December 2022, and follow up on the final status until 31 December 2023. Of 99 Thyroid cases. The survival rate was estimated using the Kaplan-Meier method. We reported the survival rate with 95% confidence interval. Of 99 Thyroid cancer patients, the total follow-up time was 348.9 person-years. There were 13 cases were death and corresponding the mortality rate was 3.73 per 100 person-year (95% CI; 2.16 - 6.42). The overall survival experience for Thyroid cancer of 1-3-5 years were 95.0% (95% CI; 88.29 - 97.87), 90.8% (95% CI: 82.13 - 95.34) and 90.8% (95% CI; 82.13 – 95.34) respectively. And survival experience for the type of thyroid cancer is Anaplastic Thyroid Cancer, ATC of 1-3-5 years were 50.0% (95% CI; 5.78 – 84.5), 50.0% (95% CI; 5.78 – 84.5) and 50.0% (95% CI; 5.78 – 84.5) respectively. After adjusted for gender and age. For type of thyroid cancer, patients with type of thyroid cancer was the important risk factor of mortality risk with Follicular thyroid Cancer,  Anaplastic thyroid cancer and other cancer cell types a 6.72 (Adjusted HR = 6.72, 95% CI; NA), 4.59  (Adjusted HR = 4.59, 95). % CI; NA) and 4.41 (Adjusted HR = 4.41, 95% CI; 1.06 - 1.84)  when compare to Papillary thyroid cancer respectively. In conclusion, There is an association between type of thyroid cancer and survival time. Therefore physician  should emphasis  to the type of Thyroid cancer  with treatment methods. Including being aware of the guidelines to ensure a long survival period.

Keywords: Thyroid cancer, Survival rate, Cancer registry