Development of Control and Surveillance Measures for Cosmetics in Ampoule, Vial and Syringe in Pre and Post Marketing Phase in Chiang Mai

Abstract

Objective: To develop regulatory control and surveillance measures for cosmetics in ampoule, vial, and syringe in Chiang Mai Province. Methods: This action research was conducted from October 2024 to September 2025 and comprised four phases: (1) assessment of the problem by compiling data from cosmetic applications for notification submitted through the automated system during 2022–2024 and reports from inspections of manufacturing/importation sites; (2) development of control and surveillance measures through focus group discussions and interviews with relevant authorities; (3) implementation of the measures; and (4) evaluation of outcomes. Results: All cosmetics in ampoule, vial, and syringe notified in Chiang Mai Province during 2022–2024 were imported products (n = 9). One product was identified for which the notification application did not correspond to the actual product. it was also misused through injection in aesthetic clinics. Authorities jointly developed provincial control and surveillance measures emphasizing strict enforcement of regulation, training for Food and Drug checkpoint officers, and coordination with the medical facility regulatory unit to inspect aesthetic clinics. After three months of implementation, the proportion of incomplete/incorrect notification applications decreased (from 17.91% to 12.60%). The mean time required for officers to review application decreased (from 26 days in 2022, 15 days in 2023, and 5 days in 2024 to 4 days). Cosmetic regulatory officers conducted joint inspections of aesthetic clinics with the medical facility regulatory unit, and identified inappropriate use of cosmetic products outside approved indications and use of unregistered products.  Training improved Food and Drug checkpoint officers’ knowledge regarding cosmetic products. Conclusion: Effective regulation of cosmetics in ampoule, vial, and syringe requires all relevant authorities to rigorously perform their assigned responsibilities and to implement systematic intersectoral integration to prevent potential harm to consumers.