Prevalence of Self-repackaging of Antiretroviral Therapy among HIV Patients at a Hospital in Roi Et

Abstract

Objective: To study prevalence and causes of self-repackaging of antiretroviral drugs, drug storage and awareness of drug stability after repackaging Methods: The research was a mixed method study in HIV patients aged 20 years and older who were on antiretroviral drugs for more than 6 months. The study consisted of 2 parts. Part 1 was quantitative research collecting data from 302 patients with a self-administered questionnaire on prevalence and causes of s self-repackaging of antiretroviral drugs, use of antiretroviral drugs, and awareness of drug stability after repackaging. Part 2 was qualitative research involving in-depth interviews with 30 patients on causes and patterns of repackaging, new packaging required by patients, and awareness of drug stability after repackaging. Results: 58.6% of patients repackaged antiretroviral drugs by themselves.  The most commonly used repackaging was the use of zipper bags (40.11%). The main reason for repackaging was the convenience for drug taking while with others (91.53%). 31.79% of patients suggested to have a smaller size of drug bottles. 35.90% of patients required expiration date indicated on drug label. 13.25% of patients had experienced a change in pill characteristics. 81.13% of them believed that it was caused by light, air, heat and humidity. 66.23% of patients believed all drugs had same storage conditions. Conclusion: 58.6% of patients have changed their antiretroviral drug packaging on their own. Patients still lack awareness on how to store drugs properly. Pharmacists should provide knowledge on drug storage and adverse effects from the use of deteriorated drugs.