Development of AI Chatbot as an Inquiry Tool for Interactions between Herbs and Cytochrome P450
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Abstract
Objective: To develop an AI chatbot as a tool for inquiring about interactions between herbs and cytochrome P450 (CYP450) and to evaluate its accuracy and appropriateness on the usage. Methods: The study consisted of 2 phases. Phase 1 involved AI-chatbot development from systematically searched and evaluated information on herbs and CYP450 interactions by connecting Google Sheet platform, Dialogflow and Line application. Phase 2 involved chatbot evaluation by ten expert pharmacists, including 7 experienced pharmacists providing consultation on interactions between herbs and drugs and 3 pharmacists with health informatics expertise. Results: The developed AI chatbot was able to respond to questions on interactions between herbs and 5 isoforms of CYP450 including CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19. Evaluation of the chatbot on five aspects including functional requirement test, usability test, result test, anticipated benefits from using the chatbot, and overall satisfaction showed a high overall average score (4.44 ± 0.60 from the full score of 5. The highest average score was found on usability test (4.53 ± 0.52). Conclusion: The AI chatbot can be used as an inquiring tool about interactions between herbs and CYP450 with a high level of satisfaction. Suggestions from experts can be incorporated to enhance the chatbot's ability to provide comprehensive answers according to users' needs.
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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