Quality of life and Service Deliveries for Antiretroviral Drugs among People with Stable HIV Disease: A Comparative Analysis
Article Sidebar
Main Article Content
Abstract
Objective: To study the quality of life and its relationship with and service deliveries for antiretroviral drugs among people with stable HIV disease in Rajavithi Hospital. Methods: This cross-sectional analytical study collected data from HIV-infected people with antiretroviral therapy and stable conditions of disease who received treatment and had relevant information in their medical records between March 1 and December 31, 2022. There were 3 service deliveries for antiretroviral drugs including 1) receiving drugs by attending a physician’s appointment, 2) regular medication refill with a pharmacist, and 3) regularly receiving medication through postal delivery. Quality of life measuring tool was Thai version of the brief World Health Organization Quality of Life Scale for HIV patients. Results: A total of 464 HIV-infected patients participated in the study, comprising 161 of those receiving medication after attending physician appointment (34.7 percent), 164 of those with medication refills from a pharmacist (35.3%), and 139 of those with postal drug delivery (30.0%). Subjects were 320 males (68.9%) with mean age of 43.8±9.7 years. The mean overall quality of life was 110.8±16.9 (full score of 155). People living with HIV with postal drug delivery had a higher quality of life score than those who received drugs after physician visits by 4.66 points (95%CI 0.58, 8.74), which was statistically significant (P=0.025). However, it was found that HIV-infected patients with medication refill with a pharmacist had no difference in quality of life scores from those receiving drug after physician visits when controlling for the influence of confounding variables. Conclusion: Quality of life scores among stable HIV-infected patients receiving medication through postal delivery was higher than those who received medication after physician visits. Therefore, stable HIV-infected patients should participate in postal drug delivery.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
Joint United Nations Program on HIV/AIDs (UNAIDS), World Health Organization (WHO). Aids by the numbers [online]. 2021 [cited Nov 9, 2021]. Available from: www.unaids.org/en.
Thailand HIV Information Collection Center Division of AIDS and Sexually Transmitted Diseases. Estimates of HIV infection: AIDS epidemic model: AEM updated [online]. 2022 [cited Mar 15, 2023]. Available from: www.hivhub.ddc.moph.go.th/epidemic .php.
National AIDS Prevention and Alleviation Committee Thailand. National strategy for ending AIDS 2017-2030. Bangkok: NC Concept; 2017.
Bureau of AIDS, Tuberculosis and STIs Department of Disease Control, Thailand. Thailand national guideline on HIV/AIDs treatment and prevention 2021/2022. Bangkok: Aksorn Graphic and Design Publishing; 2022.
Thai-US Cooperation Center for Public Health Division of AIDS and Sexually Transmitted Diseases Department of Disease Control. Guidelines for the provision of antiretroviral therapy services for people with stable symptoms of HIV infection with service users as the center in the context of health service units in Thailand. Bangkok: Radiation Company; 2020.
Duangngam P. Level of quality of life and factors effecting quality of life among HIV Infected and AIDS patients received antiretroviral drugs in community hospitals, Trang [master thesis]. Department of Health Systems Management: Thaksin University; 2012.
HIV/AIDS Quality of Life Group. WHOQOL-HIV instrument. Geneva: World Health Organization; 2002.
Meemon N, Paek SC, Yenchai D, Wan TT. Application of the WHOQOL-HIV-BREF questionnaire in HIV-infected Thai patients: Reliability and validity of the instrument. J Assoc Nurses AIDS Care 2016; 27: 698-708.
Medical Records and Statistics Information Techno- logy Group. Annual statistical report of Rajavithi Hospital [online]. 2020 [cited Nov 8, 2021]. Available from: www.rajavithi.go.th/rj/?cat=76.
Outpatient Pharmacy Department. Service profile in Rajavithi Hospital [online]. 2022 [cited Dec 15, 2022]. Available from: www.rajavithi.go.th/rj/tqm/.
Daniel, Wayne W. Biostatistics: A foundation of analysis in the health sciences. 6th ed. New York: John Wiley and Sons; 1995.
BBC Thai. The new generation living with HIV reveals obstacles in the working life of "positive people" [online]. 2018 [cited Nov 27, 2022]. Available from: www.bbc.com/thai/thailand -55172053.
Kunawaradisai N, Dawnvongyad N, Wannathong K, Moonsrikaew N, Thaiyanan S.Quality of life of HIV infected and AIDS patients in Ubon Ratchathani. Isan Journal of Pharmaceutical Sciences 2016; 12: 21-32.
Aninlabon W, Prasertchai A, Geerapong P. A comparison of quality of life among HIV/AIDs patients attending government hospitals. Journal of the Department of Medical Services 2019; 44: 120-9.
Lamaisakul G. Health-related quality of life amongst persons living with HIV/AIDS receiving antiretroviral drug at the secondary level hospital in Samut Sakhon Province [master thesis]. Bangkok: Christian University; 2012.
Tanboonyuen P, Leelaknaveera Y, Homsin P. Quality of life predictors of people living with HIV/AIDs. Journal of Public Health Nursing. 2015; 29: 80-97.
Phaktipat P, Kingphaiklang M, Cherdchaiyaphum W, Kimal W, Thangthonglang C, Sramunee K. Factors affecting CD4 levels and quality of life of HIV infected persons. Journal of Science & Technology MSU 2017; 36: 561-71.
Dawvongyad N. Quality of life, satisfaction of service and viral load suppression of HIV infected patients with differentiated care service refill clinic Sunprasittiprasong Hospital. AIDS Journal 2021; 33: 102-10.
Leenwiphat N, Khotphuwiang T. Quality of life among people living with HIV received antiretroviral drugs in Khon Kaen province. Journal of the Office of DPC 7 Khon Kaen. 2019; 27: 1-11.
Huang L, Li L, Zhang Y, Li H, Li X, Wang H. Self-efficacy, medication adherence, and quality of life among people living with HIV in Hunan Province of China: a questionnaire survey. J Assoc Nurses AIDS Care 2013; 24: 145–53.
Jiwpanya W, Makkunchorn J, Tadsreepeeradol N. The role of social groups is affecting for quality of life of HIV case: The case study of Sawanpracharak Hospital, Nakhon Sawan province. Thai AIDS Journal 2022; 34: 171-83.
Rattanapan P, Phetcharun P, Suriya S. Develop ment of mail-order pharmacy system for hypertensive patients in era of coronavirus disease 2019 pandemic. Chiangrai Medical Journal 2020; 12: 48-66.
Apipatkan N, Thanrittaweeporn K, Wonginyu K, Sanprasert S. Efficiency development of drug delivery system in the new normal model of the pharmacy unit dental hospital faculty of dentistry Khon Kaen University in the situation of the epidemic of COVID 19. The 13th National Academic Conference, Nakhon Pathom Rajabhat University: Nakhon Pathom; 8-9 July 2021.
