Effectiveness of Multidisciplinary Approach on Quality of Life and Drug Related Problems in Diabetes Mellitus and/or Hypertensive Patients Diagnosed with Chronic Kidney Disease

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Sunanchanok Namjaidee
Ampornpan Theeranutr
Nantawan Poonaovarat
Anootsara Namsanga
Sudaporn Thaitavaruk
Duangjai Adisuksodsai
Suphalak Wongma
Nuananong Sutchom
Sunee Lertsinudom

Abstract

Objective: To evaluate health-related quality of life (QOL) and drug related problems (DRPs) in patients receiving care from a multidisciplinary chronic kidney disease (CKD) clinic with pharmacist providing counseling on drugs and self-management to control risk factors and identifying DRPs. Method: First part of the study was a prospective descriptive study to investigate DRPs and QOL among patients before receiving treatment from the CKD clinic. Second part of the study was a quasi-experimental study to evaluate QOL changes among patients receiving care from the multidisciplinary CKD clinic. Primary outcomes in the study were DRPs and QOL as measured by the EQ-5D-5L. Results: The study included 234 CKD patients with an average age of 64.53±10.12 years. The most common comorbidity was hypertension. A total of 134 DRPs in CKD patients stage 1-2 were identified, with taking fewer medications than prescribed by physicians or missed doses as the most common one (77.61%). The identified DRPs were addressed and managed mainly at the patients by drug counseling. Most recommendations for resolving DRPs were accepted and followed. The outcomes were most DRPs being resolved. Average utility score of CKD patients before participating in the study was 0.9526±0.0617. At month 3, utility score of CKD patients in stages 1-2 and 3b-3b significantly increased (P=0.044 and <0.001, respectively). At month 6, utility score of CKD patients in stages 4-5 significantly increased (P=0.005). Conclusion: The provision of care and advices for CKD patients by pharmacists, in collaboration with a multidisciplinary healthcare team, could resolve DRPs and significantly improve utility score among patients with stage 3-5 kidney disease.

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Research Articles

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