Rational Use of Antibiotics in Fresh Traumatic Wounds: A Case of Community Hospital in Khon Kaen
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Abstract
Objective: To determine the prevalence of antibiotic prescribing in fresh traumatic wound, evaluate such antibiotic uses according to the criteria on rational drug use and the prevalence of wound infection after treatment. Methods: This prospective study was conducted in patients with fresh traumatic wound from accident at Pueai Noi Hospital, Khon Kaen province between December 1, 2019 and May 31, 2020. The study collected the data from electronic medical records and patient interviews including patients’ demography, wound characteristics, medication treatment and clinical outcomes at 14 days after treatment, i.e., wound healing and wound infection. Results: A total of 360 participants were recruited in this study. Antibiotics were prescribed in 37.5% of all participants. Most commonly used antibiotics was dicloxacillin (63.7%). Average duration of antibiotic use was 5.1 ± 1.6 days. The rate of rational antibiotic prescribing was 30.8%. 249 irrational uses of antibiotics composed of failure to prescribe necessary drugs, inappropriate duration of treatment, unnecessary antibiotic prescribing, and inappropriate choices of drugs in 54.6, 27.7, 16.1 and 1.6% of patients, respectively. Conclusion: Percentage of antibiotic use in patients with fresh traumatic wounds in the hospital complied with the criteria on rational drug use set at less than 40%. However, the majority of prescribing was considered irrational. The rate of wound infection was low.
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ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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