Clinical Profiles and Mortality Risk Factors in Pediatric Acute Respiratory Distress Syndrome
Pediatric Acute Respiratory Distress Syndrome
Keywords:
pediatric acute respiratory distress syndrome, clinical profile, mortality risk factorAbstract
Pediatric acute respiratory distress syndrome (PARDS) is a severe disease with a high mortality rate. Diagnosis and treatment guidelines have been improved specifically for pediatric patients under the Pediatric Acute Lung Injury Consensus Conference (PALICC), which are internationally recognized and followed. This retrospective study analyzed clinical data and mortality risk factors in PARDS patients from January 1st, 2016, to December 31st, 2019. A total 53 PARDS patients were identified, with 32 (60.4%) being male. The main cause of PARDS was direct lung injury in 47 patients (88.7%) and the 5-year average mortality rate within 28 days was 52.8%. Factors which significantly associated with mortality included disease severity, as measured by OI and OSI, PRISM III scores, PELOD-2 scores, organ failure (especially disseminated intravascular coagulation and septic shock), blood lactate levels and the amount of vasoactive medication required. The study concludes that the mortality rate for PARDS patients in this hospital is high, like the other developing countries. The patient who encounters the risk factors should receive close monitoring or consideration for additional treatment options.
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