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Incomplete oral antibiotic usage is the major problem of drug administration, cause treatment failure or drug resistant. This quasi-experimental research had aimed to examine the effects of behaviour-change program on incomplete oral antibiotics administration in respiratory tract infection patients in Bangrakam Hospital, Phitsanulok province, Thailand. The sample were 60 in-patients of respiratory infection that divided into experimental group and control group that each group was 30 subjects. The experimental group received the behaviour change program that application of a Health Belief Model to modify behavior of the patients who took under-dosage of antibiotics. The control group received standard care. Data were collected by using interview form before and after intervention in both groups. Data analysis was performed by using percentage, mean, standard deviation, independent t-test and paired t-test. Significant level was set at 0.05. Results revealed that after the experimentation, the experimental group had mean scores regarding perceived susceptibility of health risk, severity of respiratory infection form incomplete dosage of antibiotics, perceived benefits and barrier of complete oral antibiotics, knowledge of antibiotics and complete oral antibiotics administration behaviours in treatment of respiratory tract infection, significantly higher than that before the program. The experimental group also had mean scores of all variable significantly higher than that of the control group. Therefore, the behaviour change program on incomplete oral antibiotics administration in respiratory tract infection is effective to modify behaviour of patients who took incomplete dosage of antibiotics. The health personnel can apply this program for reduce problem of incomplete oral antibiotics administration
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