Study of Symptoms and Factors Affecting the Severity of COVID-19 in Children Admitted to Inburi Hospital Singburi Province
Keywords:
Symptoms, Factors affecting the severity, Covid-19 in childrenAbstract
Introduction and method: In early 2021, the World Health Organization ranked COVID-19 at the highest level of outbreak after its first epidemic in China. To gain more insight regarding how to treat, monitor, and prevent COVID-19-associated complications in children in local settings, a retrospective study of COVID-19 symptoms and associated risk factors was conducted in Inburi Hospital, Singburi, Thailand using data from medical records of 241 pediatric patients between October 1st, 2020 and March 31st, 2022. Their characteristics including age, sex, shape, underlying disease, symptoms, chest gradiographs, and laboratory results were reported using descriptive statistics while Chi-square, Fisher's exact test and logistic regression were used for comparing and identifying associated factors for COVID-19 severity.
Results: 53.5% of the patients were male and about 1/3 aged 1 to less than 5 years old. 59.3% of the patients received favipiravir. Concerning COVID-19 severity, 16.2% and 1.7% of the patients had moderate and severe illness, respectively. Factors associated with moderate to severe illness were age less than 1 year old (adjusted OR 4.25; 95%CI 1.24-14.52, p=.021), fever 38°C to less than 39°C (adjusted OR 8.70; 95% CI 3.13-24.16, p<.001), fever 39°C or higher (adjusted OR 4.70; 95% CI 1.31-16.79, p=.017) and vomiting (adjusted OR 4.35; 95% CI 1.52-12.50, p=.006).
Conclusion: Age less than 1 year old, fever 38°C or higher and vomiting were considered risk factors for an increase severity of COVID-19 in children. Therefore, it is advised to early intervene and closely monitor patients with these characteristics to prevent and alleviate disease progression and complications.
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ณัฐ อารยะพงษ์, อาการแสดงและปัจจัยที่มีผลต่อความรุนแรงของโรคโควิด 19 ในเด็ก, วารสารการแพทย์โรงพยาบาลศรีสะเกษ สุรินทร์ บุรีรัมย์ 2564; 3 :663-74.
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