Risk Factors Affecting Transient Tachypnea of the Newborn in Singburi Hospital
Keywords:
Transient Tachypnea, Newborn, RiskAbstract
Background: Transient Tachypnea of the Newborn (TTN) is a common respiratory distress problem in the newborn. Previous studies revealed that cesarean section, male, LGA, LBW, preterm birth, twins, maternal diabetes mellitus, and asthma were risk factors of TTN. However, in Thailand, controversy surrounds these risk factors.
Objective: To study risk factors of TTN in the newborn delivered at Singburi Hospital and investigate optimal gestational ages for elective cesarean section
Methods: This case-control study was conducted in the newborn delivered at Singburi Hospital during 2012-2020. A total of 184 newly born infants were categorized into 2 groups: 92 cases (TTN) and 92 cases (non-TTN).
Results: 68.5% of the newborn with TTN were male infants with an average gestational age of 37.57 (± 1.73) weeks. 28.3% were preterm infants. 25% and 14.1% were LGA and LBW infants, respectively. Most of them (81.5%) were delivered through cesarean section and 29.3% were delivered through elective C/S. The 1-minute and 5-minute Apgar scores were 9.08 (±1.19) and 9.74 (± 0.55), respectively. 22.8% and 1.1% were found to have mothers with Maternal DM and asthma, respectively. The average length of stay was 6.72 (± 3.65) days. Male, preterm birth, and emergency and elective C/S were significantly associated with TTN and could increase the risk factors of TTN by 2.95, 4.53, 2.32 and 5.65 times, respectively, greater than non-TTN infants. A minimum of 39 gestational weeks was a statistically significant protective factor against TTN (OR 0.39, 95%CI =0.18-0.83, P=0.007).
Conclusion: The risk factors of TTN in infants delivered at Singburi Hospital included male, preterm birth, emergency and elective cesarean section. Therefore, elective cesarean section was recommended to perform after a minimum of 39 gestational weeks.
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