Outcome of acute stroke treatment with intravenous thrombolytic drug in Singburi Hospital

Abstract

Objectives: To study clinical outcome after treated with intravenous thrombolytic drug in acute ischemic stroke in Singburi Hospital .The secondary objective was to study factor affecting good outcome patients. A retrospective study of data from medical records of patients diagnosed with acute stroke treated with intravenous thrombolytic drugs admitted to Singburi Hospital. During the period from 1 January 2016–30 April 2020, the basic information of the underlying disease is collected. 98 patients who received intravenous thrombosis medications for up to 3 months analyzed the data using descriptive statistics, average, percentage, Mann whitney U Test and logistical regression analysis. Results: Seventy-four patients, age 41-83 years old, an average age 64.0±10.9 years old, good outcome after treated with intravenous thrombolytic drugs was 49 patients (66.2%), An average onset to door time 106.1±49.9 minutes. An average door to needle time 64.4±28.5 minutes. An average onset to needle time 171.0±52.2 minutes. An median NIHSS 8. From the study, factors associated with good outcome were Triglyceride greater than 150 mg/dl and NIHSS at ER <10. Conclusions: Almost outcome of treatement with intravenous thrombolytic drug in acute ischemic stroke is good outcome about 66.2 percent. Factors associated with good outcome were triglyceride greater than 150 mg/dl and NIHSS at ER <10.