Effectiveness of palliative care in late-stage lung cancer compared with standard care, Chiangrai Prachanukroh Hospital
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Abstract
Background: Palliative care is effective in caring for patients under life-threatening conditions, improving the quality of life for patients and their families, reducing medical expenses, and increasing service satisfaction. However, there have been no recent studies on the effectiveness of palliative care in patients with late-stage lung cancer at Chiangrai Prachanukroh Hospital. This study aimed to enhance operational efficiency and increase patient care potential at the hospital's palliative care center.
Objective: To Compare the effectiveness of palliative care in patients with late-stage lung cancer with standard care.
Methods: This retrospective cohort study analyzed patients with late-stage lung cancer treated at Chiangrai Prachanukroh Hospital who passed away during the fiscal year 2021–2022. The subject included 214 cases, divided into 170 cases in the palliative group and a standard group bout 44 cases without palliative care consultation. Outcomes were compared, including symptom assessment, receipt of strong opioids, participating in family conferences, ICU admissions, deaths at preferred locations, and last direct medical costs before death.
Results: The palliative care group received effectively assessed and managed symptoms compared to the standard group (p < 0.001). They received strong opioids for pain control more frequently than the standard group and underwent fewer invasive procedures, such as endotracheal intubation, defibrillation, inotropic support, and ICU admissions. The palliative care group engaged in advance care planning and family conferences more often than the standard group.
The places of death of patients in both groups were significantly different. Most of the patients in the palliative care group (57.40%) died in their preferences place, meanwhile, the majority (84.09%) of the standard care did not decide on the place of death. Direct medical expenses during the last admission in the palliative group decreased by 9,005.94 Baht compared to the standard group.
Conclusions and recommendations: Palliative care for late-stage lung cancer patients is effective in evaluating and managing distressing symptoms with strong opioids, planning care, and allowing patients to choose their preferred place of death. Therefore, it is imperative to further implement the palliative care model for this particular cohort of patients.
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References
who.int[internet]. Palliative care key fact;2020[update 2020 Aug 8; cited 2021 Nov 16] Available from: https://www.who.int/news-room/fact-sheets/detail/palliative-care
Thapanakulsuk K, Saleekun S, Abhisitthiwasana N, Thiammok M. Advanced care planning for peaceful death. Journal of Boromarajonani College of Nursing. 2017;33(3):138-45.
Lertsanguansinchai P , Nuchprayoon I , Chatkaew P, Sitthiphan C, Editors. End of life care improving care of the dying. 2nd ed. Bangkok. Aksorn Samphan Printing House; 2007.
Nakwiroj K, editor. Handbook for end-of-life care and family. Nonthaburi: Beyond Enterprise; 2016.
World Health Organization [internet]. WHO Definition of palliative care. [update 2020 ; cited 2020 Oct 24]Available from:https://www.who.int/cancer/palliative/definition/en/.
National Cancer Prevention and Control Plan Committee. National Cancer Control Program National Cancer Control Program (2018-2022). Nonthaburi: Department of Medical Services Ministry of Public Health; 2018.
Department of Medical Services, Ministry of Public Health. Handbook of palliative and end-stage care (for medical personnel). Bangkok:Veterans Welfare Organization under the Royal Patronage; 2020.
Department of Medical Services, Ministry of Public Health. List disease of palliative care and functional unit. Bangkok: Art Qualified; 2016.
Board of Directors for the preparation of the 12th National Health Development Plan (2017-2021) Ministry of Public Health. Drafting the 12th National Health Development Plan (2017-2021) [internet].October 2016.[cited on 11 Oct. 2020] Available from: http://wops.moph.go.th/ops/oic/data/20161115144754_1_.pdf
Foundation of Thai Gerontology Research and Development Institute. Situation of the Thai elderly 2020. Nakhon Pathom: Institute for Population and Social Research. Mahidol University; 2021.
Imsamran V, Chaiweerawatana A, Thanasitthichai S, Laowahutanon P, Sangkrajang S, Supa-attakorn P, et al. Cancer. In Makornsarn C, editors. Thailand Medical Services Profile 2011-2014. Nonthaburi: Department of Medical Services, Ministry of Public Health; 2014. p.5-21.
Annual report, Medical information center, Chiangraiprachanukroh hospital , Fiscal year 2021-2022
Elsayem A, Swint K, Fisch MJ, Palmer JL, Reddy S, Walker P, et al. Palliative care inpatient service in a comprehensive cancer center: clinical and financial outcomes. J Clin Oncol. 2004;22(10):2008-14.
Nevadunsky NS, Gordon S, Spoozak L, Van Arsdale A, Hou Y, Klobocista M, et al. The role and timing of palliative medicine consultation for women with gynecologic malignancies: association with end of life interventions and direct hospital costs. Gynecol Oncol. 2014;132(1):3-7.
Smith TJ, Coyne P, Cassel B, Penberthy L, Hopson A, Hager MA. A high-volume specialist palliative care unit and team may reduce in-hospital end-of-life care costs. J Palliat Med. 2003;6(5):699-705.
Morrison RS, Dietrich J, Ladwig S, Quill T, Sacco J, Tangeman J, et al. Palliative care consultation teams cut hospital costs for Medicaid beneficiaries. Health Aff (Millwood). 2011;30(3):454-63.
Morrison RS, Penrod JD, Cassel JB, Caust-Ellenbogen M, Litke A, Spragens L, et al. Cost savings associated with US hospital palliative care consultation programs. Arch Intern Med. 2008;168(16):1783-90.
Sinsuwan W, Pairojkul S, Gomutbutra P, Kongkum K, Kosuwon W. A Retrospective, single center, observational study, comparing the direct cost of end-of-life care patients with advanced cancer care: palliative care versus usual uare. J Palliat Care Med 2016;6:243.
Macmillan PJ, Chalfin B, Soleimani Fard A, Hughes S. Earlier palliative care referrals associated with reduced length of stay and hospital charges. J Palliat Med. 2020;23(1):107-11.
Brumley R, Enguidanos S, Jamison P, Seitz R, Morgenstern N, Saito S, et al. Increased satisfaction with care and lower costs: results of a randomized trial of in-home palliative care. J Am Geriatr Soc. 2007;55(7):993-1000.
Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010;363(8):733-42.
Penrod JD, Deb P, Luhrs C, Dellenbaugh C, Zhu CW, Hochman T, et al. Cost and utilization outcomes of patients receiving hospital-based palliative care consultation. J Palliat Med. 2006;9(4):855-60.
Bar-Sela G, Tur-Sinai A, Givon-Schaham N, Bentur N. Advance care planning and attainment of cancer patients' end-of-life preferences: relatives' perspective. Am J Hosp Palliat Care. 2023;40(3):322-8.
Phupradabkrit Y. [Internet]. A good death : a right that everyone should receive with practical problem.2023 [Cited 2023 Sep 8]Available from: https://www.krisdika.go.th/data/activity/act13459.pdf
Working Group on Developing Guidelines for Creating an Advance Care Plan for Thailand. Thai standards for advance care planning B.E. 2022 [Internet]. Nonthaburi: The National Health Commission Office; 2022 [updated February; cited 2023 October 9]. Available from: https://peacefuldeath.co/wp-content/uploads/2022/03/ Thai standards for advance care planning B.E. 2022