Predictive Value of Fine Needle Aspiration of Thyroid Nodules in Angthong hospital
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Abstract
BACKGROUND: The predictive values of fine needle aspiration (FNA) of thyroid nodules were variable depend on experienced clinicians and pathologists. So the predictive values of each hospital were differences.
OBJECTIVES: To determine the predictive values of FNA of thyroid nodule(s) and the rate of malignancy as defined by the Bethesda System in Angthong Hospital.
METHODS: A retrospective study was conducted by reviewing the medical records of patients with thyroid nodule(s) treated at department of Otorhinolaryngology, Angthong Hospital between July 1, 2011 and June 30, 2019. All patients had to undergo FNA before thyroid surgery.
RESULTS : There were 147 patients with the mean age of 48.1 years (range 17-72). 90.5% were female. The thyroid masses were solitary nodule in 76.2% with the most diameter of 1.5- 3 cm. FNA reports revealed the positive FNA in 34.01%, being malignant FNA in 14.96% and indeterminate FNA in 19.05%. 21.09% of all thyroid histopathology was reported malignancy. The sensitivity, specificity, accuracy, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio were 90.3%, 81.0%, 83.0%, 56.0%, 96.9%, 4.76 and 0.12 respectively. The percentage of malignancy in each cytology group from 1st to 6th were 13.33, 1.22, 10, 26.67, 66.67 and 94.45 respectively.
CONCLUSIONS AND DISCUSSIONS: The predictive values and the rate of malignancy of FNA of thyroid nodules in Angthong Hospital were similar to the results of other hospitals. So these values of FNA should be able to be used as a reference for management of thyroid nodule(s) in Angthong Hospital.
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