Experiences of Patients with Major Depressive Disorder Regarding Medication Adherence: A Qualitative Study
Keywords:
experiences of patients with major depressive disorder, medication adherence, a qualitative studyAbstract
This study aimed to explore the experiences of patients with depression regarding medication adherence. A qualitative phenomenological research design was employed. The participants were 15 patients, diagnosed with depression by psychiatrists using DSM-5 criteria, who had prior experience with antidepressant medication. Participants were selected purposively. Data were collected through in-depth, semi-structured interviews conducted between August and October 2025 and were analyzed using content analysis. The results revealed four key aspects: (1) Perceptions of medication use: Patients revealed an awareness of using medication to control emotions, which resulted in consistent medication-taking behavior as part of their daily routine. (2) Factors influencing medication adherence: Family members played a supportive role in helping patients take their medication, while healthcare professionals provided knowledge and closely monitored their symptoms. (3) Barriers to medication adherence: Patients expressed fears of becoming dependent on medication, held beliefs that mental illness could be cured without medication, and lacked adequate understanding of depression. (4) Outcomes of medication adherence: Antidepressants enabled patients to better control their symptoms and emotions, resulting in improved quality of life, the ability to resume social roles, and a sense of self-worth through successful self-management. In conclusion, patients with depression exhibit diverse experiences and perspectives regarding medication use, encompassing both perceived benefits and limitations.
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