Factors Predicting Self-Management among Patients Receiving Wafarin
Main Article Content
Abstract
This predictive correlational study aimed to identify factors predicting self-management behaviors among outpatients receiving warfarin treatment at the Warfarin Clinic of Lampang Hospital. A sample of 370 patients was recruited, with data collected between April and June 2024. Research instruments included the personal and health information questionnaire, the warfarin knowledge questionnaire, the health literacy questionnaire for warfarin patients, and the self-management behavior questionnaire. These instruments were validated for content and reliability, yielding coefficients of .90, .76, and .87, respectively. Data analysis involved descriptive statistics and Multiple Regression Analysis.
The findings revealed that: 1) Overall self- management behaviors were rated at a moderate level ( =93.43, SD=13.93). The subdomains of medical management, daily life role management, and emotional management also scored at moderate levels ( =57.17 SD=9.02, =20.30 SD=4.22 and =15.97 SD =3.64, respectively). 2) Significant predictors of self-management behaviors included vision ability, and knowledge of warfarin (p<.001). Health literacy was also a significant predictor (p<.05). Among these factors, vision ability demonstrated the highest predictive power (Beta = .469).
Nurses should be encouraged to routinely assess and strengthen patients’ warfarin related knowledge, health literacy, and visual ability in order to optimize self-management behaviors among individuals receiving warfarin therapy.
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Journal of Nursing and Health Science Research attribution-non-commercial 4.0 international (CC BY-NC 4.0). For more detail please visit https://creativecommons.org/licenses/by-nc/4.0/ . The ideas and opinions expressed in the Journal of Nursing and Health Science Research are those of the authors and not necessarily those of the editor .
References
Best, J. W., & Kahn, J. V. (2006). Research in education (10th ed.). Pearson Education Inc.
Chasuwan, K., Tamdee, D., & Panuthai, S. (2023). Factors predicting self-management among
older persons with hypertension. The Southern College Network Journal of Nursing and Public Health, 10(1), 136-152. (in Thai)
Chumkasergulkij, N., Sukprasert, P., & Nakorn, W. (2021). Factors influencing health literacy and
self-management behavior in elderly patients with hypertension. Journal of Clinical Nursing, 45(4), 76–85. (in Thai)
Cronbach, L. J. (1970). Essentials of Psychological Testing. New York: Harper & Row.
De Caterina, R., Tognoni, G., & Santoro, A. (2020). The role of anticoagulation therapy in preventing cardiovascular events: Current status and future directions. International Journal of Cardiology, 314, 113–120. https://doi.org/10.1016/j.ijcard.2020.02.064
Iftikhal, A., & Srisawat, S. (2023). Health literacy factors related to health behavior among elderly in Sakon Nakhon Province. KKU Journal for Public Health Research, 16(2), 35-37.
Jansrithong,P.,& Choowattanapakorn,T.(2018). Factors Predicting Self Management in Older Persons with Acute Coronary Syndrom in TerialryHospitals, Bangkok. Journal of NursingScience Chulalongkorn University,Vol. 30 No. 2 May-August. (in Thai)
Jiang, W., Chen, P., & Tan, Y. (2021). The impact of anticoagulant therapy in preventing thromboembolic events in atrial fibrillation: A review of current literature. Journal of Clinical Nursing, 30(9–10), 1361–1369.
Kaewdamkeung, K., & Chunhasophak, J. (2021). Health literacy and self-management behaviors in patients on warfarin. Nursing Journal of Health Sciences, 23(1), 41–50. (in Thai)
Kim, H., Lee, K., & Lee, J. (2018). Health literacy and self-management in older adults: A systematic review. Journal of Geriatric Nursing, 39(1), 25–33.
Lampang Hospital Data and Statistics Center. (2022). Annual report 2022, Lampang Hospital.
http://www.lph.go.th/inforlpng/images/report/2565. (in Thai)
Kuder, G. F., & Richardson, M. W. (1937). The theory of the estimation of test reliability. Psychometrika, 2(3), 151–160. https://doi.org/10.1007/BF02288391
Merenda, T., Depasse, F., & Patris, S. (2025). The impact of simulated visual impairment on medication use process: A study with healthy volunteers. Exploratory Research in Clinical and Social Pharmacy, 18,https://doi.org/10.1016/j.rcsop.2025.100581
Minden,P.,& Varitsaku,R.(2022). Relationships Between Knowledge, Self-Efficacy, Self-Regulation,Social Support, and Self-Management Behavior Regarding Fluid Volume Overload in Chronic Heart Failure Patients. Journal of The Royal Thai Army Nurses, Vol. 23 No.3 September - December 2022. (in Thai)
Nanthamongkolchai, S., Lertwattanarak, K., & Wongpakaran, N. (2020). Impact of visual impairment on self-management behavior in
elderly patients: A cross-sectional study. Journal of Rehabilitation Research, 58(3), 121–128. (in Thai)
Nutbeam, D. (2008). The evolving concept of health literacy. Social Science & Medicine, 67(12), 2072–2078.
Paisarntuksin, P., Khumngeon, A., Yanachai, J., & Khenhong, N. (2018). Relationship between knowledge, social support and self-
management in atrial fibrillation patients receiving anti-coagulants. Nursing Public Health and Education Journal. 19(2). 49-57.
(in Thai)
Panompong, K., & Tonhongsa, P. (2021). Factors influencing INR levels in patients taking warfarin: A cohort study. Journal of Clinical
Nursing, 34(6), 1264–1272. (in Thai)
Polit, D. F. (1996). Data analysis and statistics for nursing research. Philadelphia: Appleton & Lang.
Pomthong, K., Masingboon, K., & Kunsongkeit, W. (2019). Factors influencing foot care behaviors among type II diabetes mellitus patients at risk for diabetic foot ulcer. Journal of Nursing and Health Care, 37(4), October–December,109-118. (in Thai)
Poungkaew, A., Tankumpuan, T., Riangkam, C., Kongwatcharapong, J., Daekunthod, T., Sriyayang, K., Krittayaphong, R., & Koirala, B.
(2024). Warfarin adherence and its associated factors in Thai older adults with atrial fibrillation. Journal of Multidisciplinary Healthcare, 17, 4455–4464.
Santaweesook, S., Malathum, P., & Sutti, N. (2023). Self-care behaviors of medication use and medication use problems in old people
with chronic diseases. Nurs Res Inno J, 29(3), 332-348. (in Thai)
Sheng, Y., Luo, Y., & Lin, S. (2023). Self-management behaviors of patients on warfarin: An overview of current practices and challenges.
Journal of Nursing and Health Studies, 9(1), 55–64.
Sorensen, K., Pelikan, J., & Röthlin, F. (2021). Health literacy and health outcomes: The importance of functional health literacy in chronic
disease management. International Journal of Public Health, 66, 567–574.
Sørensen, K., Van den Broucke, S., & Fullam, J. (2012). Health literacy and public health: A systematic review and integration of definitions and models. BMC Public Health, 12(1), 80–90.
Sratongprom, C., & Suriruk, S. (2020). The effect of drug label pictures on drug use behavior in the elderly with high blood pressure that
cannot blood pressure in the area of Ban Nong Ri health promotion hospital Ban Luek Sub-district, Photharam District, Ratchaburi
Province. Journal of Council of Community Public Health, 2(2), 14-26. (in Thai)
Suwannasa,C.,& W, Kangchai.,& Rattanajarana,S.(2023). Factors related to self-Management behaviors among older adults With
Coronary Artery Disease. Journal of Faculty of Nursing Burapha University., Volume 31 No. 1 (Jan - Mar) ,72-80. (in Thai)
Thai Heart Association. (2020). Guidelines for anticoagulation therapy in cardiovascular diseases. Journal of the Thai Heart Association,
(2), 65–71. (in Thai)
Thamthinnano, W. (2017). Pharmacokinetics and pharmacodynamics of warfarin: Clinical implications in patient management. Journal
of the Thai Nursing Council, 33(2), 150–157. (in Thai)
Vanichbuncha,K., & Vanichbuncha, T.(2017). SPSS for window.Bangkok: Rongphim Samlada. (in Thai)