Lipid Profile Test and Factors Associated with TC/HDL-C Ratio among Dyslipidemia Population in Muang District, Trang Province
Keywords:
Lipid Profiles, TC/HDL-C, Lipid Ratios, Knowledge, Attitude, Food Consumption BehaviorsAbstract
This cross-sectional study aimed to analyze lipid profiles among dyslipidemia patients and to study factors associated with total cholesterol and HDL-C ratio (TC/HDL-C) in Muang District, Trang Province. Sample was 393 dyslipidemia patients. Data collection was done using the lipid profiles of the participants and a questionnaire for general information but also about knowledge, attitude and food consumption behaviors of the participants. Descriptive statistics such as frequency and percentage were used in the analysis. In addition, multiple logistic regression was used to assess factors related to TC/HDL-C ratio. Most of the participants were female (74%), with an average age of 64.63 years old (SD=12.01) and married (66.20%). In addition, more than half of them had normal body mass index (58%). About half of the participants had the results of classical lipid profiles—LDL-C and TC above normal level (90.58% and 88.55%, respectively). However, HDL-C was at a normal level. Moreover, about half of them had higher level of TC/HDL-C ratio (50.9%), followed by LDL-C/HDL-C and TG/HDL-C ratios as half of them were at a normal level. When sub-analysis was conducted in the group that had good knowledge, attitude and food consumption behaviors, only the good knowledge group had a higher proportion of normal level of TC/HDL-C ratio, while other groups had a less normal level proportion. Lastly, factors associated with TC/HDL-C ratio were female (OR=2.46, p-value=0.01) and knowledge (OR=0.58, p-value=0.02) that was a protective factor.
In conclusion, most of the participants in this study still had abnormal levels of both classical lipid profiles and lipid ratios. Therefore, better method of providing more knowledge about factors that may affect lipid profiles as a protective factor should be applied particularly in female and a good follow up system should be also applied to them in the future in order to change their behaviors and improve their lipid profiles and ratios.
References
Anand, S. S., Yusuf, S., Jacobs, R., Davis, A. D., Yi, Q., Gerstein, H., et al. (2001). Risk Factors, Atherosclerosis, and Cardiovascular Disease among Aboriginal People in Canada: the Study of Health Assessment and Risk Evaluation in Aboriginal Peoples (SHARE-AP). Lancet, 6;358(9288): 1147-53.
Anand, S. S., Yusuf, S., Vuksan, V., Devanesen, S., Teo, K. K., Montague, P. A., et al. (2000). Differences in Risk Factors, Atherosclerosis, and Cardiovascular Disease Between Ethnic Groups in Canada: the Study of Health Assessment and Risk in Ethnic Groups (SHARE). Lancet, Jul 22;356(9226): 279-84.
Bloom, B. S., Madaus, G. F., & Hastings, J. T. (1971). Handbook on Formative and Summative Evaluation of Student Learning. New York: McGraw-Hill.
Boonsuk, S. (2010). Knowledge, Attitude and Practice of Lipid Consumption in Patients at 7th. Health Center of Ubonratchatanee Province, Research Report: Health Promoting Hospital of 7th Health Center of Ubonratchatanee. (in Thai).
Bureau of Non Communicable Diseases, Department of Disease Control, Ministry of Public Health, (2016). Annual Report 2016. Nonthaburi. The War Veterans Organization of Thailand. (in Thai)
Castelli, W. P. (1998). Cholesterol and Lipids in the Risk of Coronary Artery Disease-the Framingham Heart Study. The Canadian Journal of Cardiology, 4Suppl(A), 5a-10a.
Da Luz, P. L., Favarato, D., Faria-Neto, J. R., Lemos, P., & Chagas, A. C. (2008). High Ratio of Triglyceride to HDL-Cholesterol Predicts Extensive Coronary Disease. Clinics, 63, 427-432.
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) (2001). Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). Jama, 16(19), 2486-97.
Foosuwan, S., Lirtmunlikaporn, S., & Singkaew, J. (2016). Factors Predicting Serum Lipid Level among Persons with Dyslipidemia in Community. Nursing Journal, 42(2), 79-89. (in Thai)
Gaziano, J. M., Hennekens, C. H., O’Donnell, C. J., Breslow, J. L., & Buring, J. E. (1997). Fasting Triglycerides, High Density Lipoprotein, and Risk of Myocardial Infarction. Circulation, 96, 2520-2525.
Grundy, S. M., Cleeman, J. I., Merz, C. N., Brewer, H. B. Jr., Clark, L. T., Hunninghake, D. B., et al. (2004). National Heart, Lung, and Blood Institute, American College of Cardiology Foundation, American Heart Association: Implication of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation, 110, 227-239.
Lee, J. S., Cheong, H. S., & Shin, H. D. (2018). Prediction of Cholesterol Ratios within a Korean Population. Royal Society Open Science, 5(1),171-204.
McGovern, P. G., Pankow, J. S., Shahar, E., Doliszny, K. M., Folsom, A. R., Blackburn, H., et al. (1996). Recent Trends in Acute Coronary Heart Disease--Mortality, Morbidity, Medical Care, and Risk Factors. The Minnesota Heart Survey Investigators. The New England journal of medicine, 334(14), 884-90.
Mirmiran, P., Mohammadi-Nasrabadi, F., Omidvar, N., Hosseini-Esfahani, F., Hamayeli-Mehrabani, H., Mehrabi, Y. et al. (2010). Nutritional Knowledge, Attitude and Practice of Teharanian Adults and TheirnRelation to Serum Lipid and Lipoproteins: Teharan Lipid and Glucose Study. Annals of Nutrition & Metabolism, 56(3), 233-40.
Nijjar, A. P., Wang, H., Quan, H., & Khan, N. A. (2010). Ethnic and Sex Differences in the Incidence of Hospitalized Acute Myocardial Infarction: British Columbia, Canada 1995-2002. BMC Cardiovascular Disorders, 19(10), 38.
Phupolpian, T. (2018). Knowledge, Attitude and Food Consumption Behavior of People with Dyslipidemia in Amphoe Mueangtrang Changwat Trang. A Specific Health Study Submitted in Partial Fulfillment of the Requirement for the Bachelor Degree in Public Health (Community Public Health). Department of Community Public Health, Sirindhorn College of Public Health, Trang. (in Thai)
Stampfer, M. J., Sacks, F. M., Salvini, S., Willett, W. C., & Henneckens, C. H. (1991). A Prospective Study of Cholesterol Apolipoproteins and the Risk of Myocardial Infarction. New Eng J Med, 325, 373-381.
Sheth, T., Nair, C., Nargundkar, M., Anand, S., & Yusuf, S. (1999). Cardiovascular and Cancer Mortality among Canadians of European, South Asian and Chinese Origin from 1979 to 1993: An Analysis of 1.2 Million Deaths. CMAJ : Canadian Medical Association journal, 161(2), 132-8.
Trang Provincial Public health Office. (2017). Report of Prevalecnce of NCDs. Retrived December 3, 2018 from: http://www.tro.moph.go.th. (in Thai)
Wilkins, R., Tjepkema, M., Mustard, C., & Choiniere, R. (2008). The Canadian Census Mortality Follow-Up Study, 1991 through 2001. Health reports, 19(3), 25-43.
Yamane, T. (1967). Statistics: An Introductory Analysis. 2nd, editor. New York: Harper & Row.
Zhang, L., Chen, S., Deng, A., Liu, X., Liang, Y., Shao, X., et al. (2015). Association Between Lipid Ratios and Insulin Resistance in a Chinese Population. PloS one, 10(1), e0116110-e.
Zhou, M., Zhu, L., Cui, X., Feng, L., Zhao, X., He, S., et al. (2016). The Triglyceride to High-Density Lipoprotein Cholesterol (TG/HDL-C) Ratio as a Predictor of Insulin Resistance but not of β Cell Function in a Chinese Population with Different Glucose Tolerance Status. Lipids in Health and Disease, 15, 104.
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