The Related Between the Amount of PM 2.5 and COPD Exacerbation in Koh Kha Hospital, Lampang
Keywords:
Particulate matter 2.5 (PM2.5), Chronic obstructive pulmonary disease (COPD), Acute exacerbationAbstract
Abstract
This is a cross-sectional analytical study with prospective data collection. The research objective is to find out the relationship between PM2.5 dust and acute exacerbations of COPD patients at Koh Kha Hospital, Lampang Province. The sample group used in this research was 909 COPD patients. The ICD 10 diagnosis code was J44.1, J44.8 and J44.9. Data was collected from 1 November 2019 to 30 September 2022. The study tools consist of personal history questionnaire, COPD patients' medical records and PM 2.5 data measured from the weather station of the Pollution Control Department. Analyze statistical data for correlation of variables with Pearson's correlation. Risk factors were compared with Odds ratio (OR). All statistical tests were conducted at a significance level of 0.05.
The results found that the number of COPD patients with acute exacerbation were directly proportional to the increased level of PM 2.5 (r=0.536, p-value < 0.001). PM 2.5 dust more than 50 µg/m3 is a risk factor for COPD patients to exacerbate (adjusted OR=1.47, 95% CI 1.12-1.94, p-value=0.006). Smoking history is also a risk factor (OR=2.30, 95% CI 1.76-3.00, p-value < 0.001).
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