Factors to indicate successful stop labor in pregnant women with preterm labor
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Abstract
BACKGROUND: Preterm birth significantly impacts infant development.
OBJECTIVE: This study aims to investigate factors associated with the success of inhibiting preterm birth in pregnant women at Chiangrai Prachanukroh Hospital, Chiangrai province.
METHODS: A retrospective cohort study was conducted on a sample group of pregnant women who received interventions to prevent preterm birth. The data were collected from hospital records and patient registries from October 2022 to September 2023. The sample consists of a study group that successfully inhibited and a group that unsuccessfully inhibited. The data were analyzed using univariable and multivariable logistic regression statistics, with a significance level set at less than 0.05.
RESULTS: The sample group comprised 149 individuals, divided into a successful intervention group (77 individuals [51.67%]) and an unsuccessful intervention group (72 individuals [48.32%]). Statistically significant factors were identified, including maternal age under 35 years (adjusted OR 5.02, 95% CI 1.75 - 14.39, p-value=0.003), cervical effacement during preterm labor less than 50% (adjusted OR 4.09, 95% CI 1.36-12.27, p-value=0.012) and cervical dilation less than or equal to 1 centimeter (adjusted OR 3.14, 95% CI 1.21-8.18, p-value=0.019). Additionally, a statistically significant trend was observed for gestational age at the first episode of preterm labor greater than or equal to 33 weeks (adjusted OR 2.20, 95% CI 1.00-4.84, p-value=0.050).
CONCLUSIONS AND RECOMMENDATIONS: Maternal age less than 35 years, cervical thinning less than 50%, and cervical dilation less than or equal to 1 centimeter are significant factors indicating success in inhibiting preterm birth in pregnant women with preterm labor. Therefore, all pregnant women, especially older than 35 years, should be educated about labor pains and should intensive care since early labor pain.
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References
Perin J, Mulick A, Yeung D, Villavicencio F, Lopez G, Strong KL, et al. Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet Child Adolesc Health. 2022;6(2):106-15.
Ohuma EO, Moller AB, Bradley E, Chakwera S, Hussain-Alkhateeb L, Lewin A, et al. National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. Lancet. 2023;402(10409):1261-71.
Percentage of Thai women who give birth prematurely in fiscal year 2567 [Internet]. Nonthaburi: Ministry of Public Health; 2024 [cited 2024 March 25]. Available from: https://hdcservice.moph.go.th/hdc/reports/report.php?source=pformated/format1.php&cat_id=1ed90bc32310b503b7ca9b32af425ae5&id=ecdbfc8b4725386c34623ce99f0f4b8d.
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics. Practice Bulletin No. 171: Management of Preterm Labor. Obstet Gynecol.
;128(4):e155-64.
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics. Practice Bulletin No. 171: Management of Preterm Labor. Obstet Gynecol.
;128(4):e155-64.
Stagnaro-Green A. Maternal thyroid disease and preterm delivery. J Clin Endocrinol Metab.
;94(1):21-5.
Toontham K, Supathaweewat S. Factors associated with preterm birth, accuracy rate and coverage rate of the clinical guideline of preterm labor and success rate in preterm uterine contraction inhibition in Mahasarakham Hospital. 2023;20:(2):75-88.
Sopajaree C. Factors predicting delaying in preterm birth among women who received tocolysis. J Thai Nurse midwife Counc. 2018;33(2):47-58.
Uatrongjit N. Predicting factors associated with preterm birth after receiving stopping preterm labor treatment. J Nakornping Hosp. 2020;10(1): เลขหน้า?
Esposito G, Mauri PA, Cipriani S, Franchi M, Corrao G, Parazzini F. Correction to: The role of maternal age on the risk of preterm birth among singletons and multiples: a retrospective cohort study in Lombardy, Northern Italy. BMC Pregnancy Childbirth. 2022;22(1):366.
Traisrisilp K, Tongsong T. Pregnancy outcomes of mothers with very advanced maternal age (40 years or more). J Med Assoc Thai. 2015;98(2):117-22.
Langen ES, Weiner SJ, Bloom SL, Rouse DJ, Varner MW, Reddy UM, et al. Association of cervical effacement with the rate of cervical change in labor among nulliparous women. Obstet Gynecol. 2016;127(3):489-95.