Amiodarone induced hypothyroidism (AIH)

Main Article Content

Nuengruethai Khumphet

Abstract

The report incidence of Amiodarone-induced hypothyroidism (AIH) ranging from 4-22 %, which may occur during therapy between 3-12 months. The risk of developing hypothyroidism is independent of the daily or cumulative dose of amiodarone. However, the risk is greater in the elderly and in female patients. Most of patients often become euthyroid within 2-4 months. Therefore, thyroid functions should be monitored at 3 months prior and after receiving amiodarone treatment. To appropriately manage treatment in individual patients.

Article Details

How to Cite
1.
Khumphet N. Amiodarone induced hypothyroidism (AIH). crmj [internet]. 2020 Jul. 12 [cited 2025 Dec. 18];12(1):93-9. available from: https://he01.tci-thaijo.org/index.php/crmjournal/article/view/231369
Section
Case Report

References

1. Goldschlager N, Epstein AE, Naccarelli GV, et al. A practical guide for clinicians who treat patients with amiodarone: 2007. Heart Rhythm 2007; 4: 1250-1259.
2. Van Erven L, Schalij MJ. Amiodarone: an effective antiarrhythmic drug with unusual side effects. Heart 2010; 96: 1593-1600.
3. Singla S, Karam P, Deshmukh AJ, et al. Review of contemporary antiarrhythmic drug therapy for maintenance of sinus rhythm in atrial fibrillation. J Cardiovasc Pharmacol Ther 2012; 17: 12-20.
4. Jafari-Fesharaki M, Scheinman MM. Adverse effects of amiodarone. PACE 1998; 21 (part I): 108-120.
5. Bartalena L, Bogazzi F, Chiovato L, et al. 2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction: 2018. Eur Thyroid J 2018; 7: 55–66.
6. Shashithej K. Narayana, David R, Woods Christoher J, et al. Management of amiodarone-related thyroid problems. Ther Adv Endocrinol Metab 2011; 2(3): 115-126.